User profiles for Vincent Grass

Vincent Grass

Technische Universität München (TUM)
Verified email at tum.de
Cited by 942

[HTML][HTML] Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

A Stukalov, V Girault, V Grass, O Karayel, V Bergant… - Nature, 2021 - nature.com
The emergence and global spread of SARS-CoV-2 has resulted in the urgent need for an in-depth
understanding of molecular functions of viral proteins and their interactions with the …

ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion

G Jocher, V Grass, SK Tschirner, L Riepler… - EMBO …, 2022 - embopress.org
The severe‐acute‐respiratory‐syndrome‐coronavirus‐2 (SARS‐CoV‐2) is the causative
agent of COVID‐19, but host cell factors contributing to COVID‐19 pathogenesis remain only …

[HTML][HTML] Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing

J Zecha, CY Lee, FP Bayer, C Meng, V Grass… - Molecular & Cellular …, 2020 - ASBMB
As the COVID-19 pandemic continues to spread, thousands of scientists around the globe
have changed research direction to understand better how the virus works and to find out how …

Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread

…, N Kneidinger, MG Stoleriu, V Grass… - Nucleic Acids …, 2022 - academic.oup.com
A promising approach to tackle the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
could be small interfering (si)RNAs. So far it is unclear, which viral replication steps …

[HTML][HTML] Disruption of disulfides within RBD of SARS‐CoV‐2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs

…, T Plaper, V Jazbec, V Bergant, V Grass… - The FASEB …, 2021 - ncbi.nlm.nih.gov
The SARS‐CoV‐2 pandemic imposed a large burden on health and society. Therapeutics
targeting different components and processes of the viral infection replication cycle are being …

Attenuation of SARS‐CoV‐2 replication and associated inflammation by concomitant targeting of viral and host cap 2'‐O‐ribose methyltransferases

V Bergant, S Yamada, V Grass, Y Tsukamoto… - The EMBO …, 2022 - embopress.org
The SARS‐CoV‐2 infection cycle is a multistage process that relies on functional interactions
between the host and the pathogen. Here, we repurposed antiviral drugs against both viral …

[HTML][HTML] Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators

…, C Urban, A Stukalov, LL Andersen, V Grass… - Nature …, 2021 - nature.com
The cell intrinsic antiviral response of multicellular organisms developed over millions of
years and critically relies on the ability to sense and eliminate viral nucleic acids. Here we use …

[PDF][PDF] Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection

KI Wagner, LM Mateyka, S Jarosch, V Grass, S Weber… - Cell reports, 2022 - cell.com
T cell immunity is crucial for control of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection and has been studied widely on a quantitative level. However, the …

[HTML][HTML] Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein

…, A Reiter, LS Wolff, CC Cheng, M Stern, V Grass… - Antiviral Research, 2021 - Elsevier
SARS-CoV-2 enters host cells after binding through its spike glycoprotein to the angiotensin-converting
enzyme 2 (ACE2) receptor. Soluble ACE2 ectodomains bind and neutralize the …

[HTML][HTML] Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting

C Gruber, L Krautner, V Bergant, V Grass, Z Ma… - Cell Discovery, 2024 - nature.com
Dear Editor, CRISPR/Cas13 systems are programmable tools for manipulating RNAs and
are used in a variety of RNA-targeting applications 1–3. Within the Cas13 family, Cas13d is …