Treatment of B-cell disorder improves renal outcome of patients with monoclonal gammopathy–associated C3 glomerulopathy

…, A François, M Le Quintrec, V Javaugue… - Blood, The Journal …, 2017 - ashpublications.org
The high frequency of monoclonal gammopathy in adult patients with C3 glomerulopathy (C3G)
emphasizes the role of monoclonal immunoglobulin (MIg) in the occurrence of renal …

[HTML][HTML] Bortezomib produces high hematological response rates with prolonged renal survival in monoclonal immunoglobulin deposition disease

C Cohen, B Royer, V Javaugue, R Szalat, K El Karoui… - Kidney International, 2015 - Elsevier
Monoclonal immunoglobulin deposition disease (MIDD) is a rare complication of plasma cell
disorders, defined by linear Congo red-negative deposits of monoclonal light chain, heavy …

Randall-type monoclonal immunoglobulin deposition disease: novel insights from a nationwide cohort study

F Joly, C Cohen, V Javaugue, S Bender… - Blood, The Journal …, 2019 - ashpublications.org
Monoclonal immunoglobulin deposition disease (MIDD) is a rare complication of B-cell
clonal disorders, defined by Congo red negative–deposits of monoclonal light chain (LCDD), …

Prognostic value of kidney biopsy in myeloma cast nephropathy: a retrospective study of 70 patients

…, S Chevret, V Javaugue… - Nephrology Dialysis …, 2016 - academic.oup.com
Background Light chain myeloma cast nephropathy (MCN) is the major cause of renal failure
in multiple myeloma and strongly impacts patient survival. The role of kidney biopsy in the …

[HTML][HTML] Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management

F Bridoux, V Javaugue, S Bender, F Leroy… - Kidney international, 2017 - Elsevier
Randall-type heavy chain deposition disease (HCDD) is a rare disorder characterized by
tissue deposition of a truncated monoclonal immunoglobulin heavy chain lacking the first …

Kidney diseases associated with monoclonal immunoglobulin M–secreting B-cell lymphoproliferative disorders: A case series of 35 patients

S Chauvet, F Bridoux, L Ecotière, V Javaugue… - American Journal of …, 2015 - Elsevier
… Author links open overlay panel Sophie Chauvet MD 1 2 , Frank Bridoux MD, PhD 1 2 3 ,
Laure Ecotière MD 1 2 , Vincent Javaugue MD 1 2 , Christophe Sirac PhD 1 3 , Bertrand Arnulf …

Long-term kidney disease outcomes in fibrillary glomerulonephritis: a case series of 27 patients

V Javaugue, A Karras, F Glowacki, B McGregor… - American journal of …, 2013 - Elsevier
Background Fibrillary glomerulonephritis (GN) is a rare disorder with poor renal prognosis.
Therapeutic strategies, particularly the use of immunosuppressive drugs, are debated. Study …

Impaired lysosomal function underlies monoclonal light chain–associated renal Fanconi syndrome

A Luciani, C Sirac, S Terryn, V Javaugue… - Journal of the …, 2016 - journals.lww.com
Monoclonal gammopathies are frequently complicated by kidney lesions that increase the
disease morbidity and mortality. In particular, abnormal Ig free light chains (LCs) may …

[HTML][HTML] The clinicopathologic characteristics of kidney diseases related to monotypic IgA deposits

…, J Pourrat, D Chauveau, JM Goujon, V Javaugue… - Kidney international, 2017 - Elsevier
Monoclonal gammopathy of renal significance (MGRS) regroups renal disorders caused by
a monoclonal immunoglobulin without overt hematological malignancy. MGRS includes …

Proliferative glomerulonephritis with monoclonal immunoglobulin deposits: a nephrologist perspective

F Bridoux, V Javaugue, SH Nasr… - Nephrology Dialysis …, 2021 - academic.oup.com
Proliferative glomerulonephritis (GN) with monoclonal immunoglobulin deposits (PGNMIDs)
is a recently described entity among the spectrum of monoclonal gammopathy of renal …