User profiles for Vineeta Bajaj
Vineeta BajajReview Editor, JoVE Verified email at jove.com Cited by 294 |
[HTML][HTML] Role of CYP1B1, MYOC, OPTN and OPTC genes in adult-onset primary open-angle glaucoma: predominance of CYP1B1 mutations in Indian patients
Purpose Mutations in the CYP1B1, MYOC, OPTN, and WDR36 genes result in glaucoma.
Given its expression in the optic nerve, it is likely a mutation in the OPTC gene is also involved …
Given its expression in the optic nerve, it is likely a mutation in the OPTC gene is also involved …
[HTML][HTML] Angiomyolipoma have common mutations in TSC2 but no other common genetic events
W Qin, V Bajaj, I Malinowska, X Lu, L MacConaill… - PLoS …, 2011 - journals.plos.org
Renal angiomyolipoma are part of the PEComa family of neoplasms, and occur both in
association with Tuberous Sclerosis Complex (TSC) and independent of that disorder. Previous …
association with Tuberous Sclerosis Complex (TSC) and independent of that disorder. Previous …
A small molecule inhibitor of fungal histone acetyltransferase Rtt109
JL da Rosa, V Bajaj, J Spoonamore… - Bioorganic & medicinal …, 2013 - Elsevier
The histone acetyltransferase Rtt109 is the sole enzyme responsible for acetylation of histone
H3 lysine 56 (H3K56) in fungal organisms. Loss of Rtt109 renders fungal cells extremely …
H3 lysine 56 (H3K56) in fungal organisms. Loss of Rtt109 renders fungal cells extremely …
A synthetic biology approach to probing nucleosome symmetry
10.7554/eLife.28836.001 The repeating subunit of chromatin, the nucleosome, includes two
copies of each of the four core histones, and several recent studies have reported that …
copies of each of the four core histones, and several recent studies have reported that …
[HTML][HTML] Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer
EM Mrozek, V Bajaj, Y Guo, IA Malinowska, J Zhang… - PLoS …, 2021 - journals.plos.org
Inactivating mutations in either TSC1 or TSC2 cause Tuberous Sclerosis Complex, an autosomal
dominant disorder, characterized by multi-system tumor and hamartoma development. …
dominant disorder, characterized by multi-system tumor and hamartoma development. …
Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS
The SLC22A18/SLC22A18AS genes are a sense–antisense pair located at human chromosome
segment 11p15.5. These genes are paternally imprinted: paternal alleles are silenced …
segment 11p15.5. These genes are paternally imprinted: paternal alleles are silenced …
Characterization of the human SLC22A18 gene promoter and its regulation by the transcription factor Sp1
SLC22A18, a poly-specific organic cation transporter, is paternally imprinted in humans and
mice. It shows loss-of-heterozygosity in childhood and adult tumors, and gain-of-imprinting …
mice. It shows loss-of-heterozygosity in childhood and adult tumors, and gain-of-imprinting …
[HTML][HTML] Paternal imprinting of the SLC22A1LS gene located in the human chromosome segment 11p15.5
Background Genomic imprinting is an epigenetic chromosomal modification in the gametes
or zygotes that results in a non-random monoallelic expression of specific autosomal genes …
or zygotes that results in a non-random monoallelic expression of specific autosomal genes …
Identification of Hsp90 inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer
EM Mrozek, V Bajaj, Y Guo, IA Malinowska, J Zhang… - bioRxiv, 2021 - biorxiv.org
Inactivating mutations in either TSC1 or TSC2 cause Tuberous Sclerosis Complex, an autosomal
dominant disorder, characterized by multi-system tumor and hamartoma development. …
dominant disorder, characterized by multi-system tumor and hamartoma development. …
Molecular Characterization Of The SLC22A18AS Gene From The Imprinted Human Chromosome Segment 11p15. 5
V Bajaj - 2011 - etd.iisc.ac.in
The imprinting status of the SLC22A18AS gene, located in the human chromosome segment
11p15.5, was studied using PCR-SSCP analysis and fetal tissues from a battery of 17 …
11p15.5, was studied using PCR-SSCP analysis and fetal tissues from a battery of 17 …