[HTML][HTML] Interferon-α2b Treatment for COVID-19
Q Zhou, V Chen, CP Shannon, XS Wei… - Frontiers in …, 2020 - frontiersin.org
The global pandemic of COVID-19 cases caused by infection with SARS-CoV-2 is ongoing,
with no approved antiviral intervention. We describe here the effects of treatment with …
with no approved antiviral intervention. We describe here the effects of treatment with …
Sputum microbiome is associated with 1-year mortality after chronic obstructive pulmonary disease hospitalizations
…, S Tam, J Yang, Z Hollander, V Chen… - American journal of …, 2019 - atsjournals.org
Rationale: Lung dysbiosis promotes airway inflammation and decreased local immunity,
potentially playing a role in the pathogenesis of acute exacerbations of chronic obstructive …
potentially playing a role in the pathogenesis of acute exacerbations of chronic obstructive …
Immunochemistry of elastotic material in sun-damaged skin
VL Chen, R Fleischmajer, E Schwartz, M Palaia… - Journal of investigative …, 1986 - Elsevier
The nature of elastotic material in sun-damaged human skin was investigated by indirect
immunofluorescence. Antibodies were used against the following components of the dermis: …
immunofluorescence. Antibodies were used against the following components of the dermis: …
Characterization of regulatory T cells in obese omental adipose tissue in humans
…, AM Pesenacker, Q Huang, V Chen… - European Journal of …, 2019 - Wiley Online Library
Obesity‐associated visceral adipose tissue (AT) inflammation promotes insulin resistance
and type 2 diabetes (T2D). In mice, lean visceral AT is populated with anti‐inflammatory cells, …
and type 2 diabetes (T2D). In mice, lean visceral AT is populated with anti‐inflammatory cells, …
[HTML][HTML] Treg gene signatures predict and measure type 1 diabetes trajectory
AM Pesenacker, V Chen, J Gillies, C Speake… - JCI insight, 2019 - ncbi.nlm.nih.gov
BACKGROUND. Multiple therapeutic strategies to restore immune regulation and slow type
1 diabetes (T1D) progression are in development and testing. A major challenge has been …
1 diabetes (T1D) progression are in development and testing. A major challenge has been …
[HTML][HTML] Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease
M Obeidat, Y Nie, V Chen, CP Shannon… - Respiratory …, 2017 - Springer
Background Chronic obstructive pulmonary disease (COPD) is currently the third leading
cause of death and there is a huge unmet clinical need to identify disease biomarkers in …
cause of death and there is a huge unmet clinical need to identify disease biomarkers in …
[HTML][HTML] A computational pipeline for the development of multi-marker bio-signature panels and ensemble classifiers
OP Günther, V Chen, GC Freue, RF Balshaw… - BMC …, 2012 - Springer
Background Biomarker panels derived separately from genomic and proteomic data and
with a variety of computational methods have demonstrated promising classification …
with a variety of computational methods have demonstrated promising classification …
[HTML][HTML] The impact of IgG subclass deficiency on the risk of mortality in hospitalized patients with COPD
Background Immunoglobulin G (IgG) deficiency increases the risk of acute exacerbations
and mortality in chronic obstructive pulmonary disease (COPD). However, the impact of IgG …
and mortality in chronic obstructive pulmonary disease (COPD). However, the impact of IgG …
Development and validation of apolipoprotein AI-associated lipoprotein proteome panel for the prediction of cholesterol efflux capacity and coronary artery disease
Z Jin, TS Collier, DLY Dai, V Chen, Z Hollander… - Clinical …, 2019 - academic.oup.com
BACKGROUND Cholesterol efflux capacity (CEC) is a measure of HDL function that, in cell-based
studies, has demonstrated an inverse association with cardiovascular disease. The …
studies, has demonstrated an inverse association with cardiovascular disease. The …
[HTML][HTML] Clinical utility of C-reactive protein to predict treatment response during cystic fibrosis pulmonary exacerbations
A Sharma, G Kirkpatrick, V Chen, K Skolnik… - PLoS …, 2017 - journals.plos.org
Rationale C-reactive protein (CRP) is a systemic marker of inflammation that correlates with
disease status in cystic fibrosis (CF). The clinical utility of CRP measurement to guide …
disease status in cystic fibrosis (CF). The clinical utility of CRP measurement to guide …