Background Genetic factors contribute to anorexia nervosa (AN); and the first genome-wide
significant locus has been identified. We describe methods and procedures for the Anorexia …

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …

We performed a comprehensive assessment of rare inherited variation in autism spectrum
disorder (ASD) by analyzing whole-genome sequences of 2,308 individuals from families with …

Eating disorders and substance use disorders frequently co‐occur. Twin studies reveal
shared genetic variance between liabilities to eating disorders and substance use, with the …

Rare mutations, including copy-number variants (CNVs), contribute significantly to autism
spectrum disorder (ASD) risk. Although their importance has been established in families with …

Background: Genetic factors contribute to anorexia nervosa (AN); and the first genome-wide
significant locus has been identified. We describe methods and procedures for the Anorexia …

Hundreds of genetic loci increasing risk for neuropsychiatric disorders have recently been
identified. This success, perhaps paradoxically, has posed challenges for therapeutic …

Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple
sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 …

The predisposition to neuropsychiatric disease involves a complex, polygenic, and pleiotropic
genetic architecture. However, little is known about how genetic variants impart brain …

Genetic risk for multiple sclerosis (MS) is thought to involve both common and rare risk alleles.
Recent GWAS and subsequent meta-analysis have established the critical role of the HLA …