APOE4 affects basal and NMDAR-mediated protein synthesis in neurons by perturbing calcium homeostasis
S Ramakrishna, V Jhaveri, SC Konings… - Journal of …, 2021 - Soc Neuroscience
Apolipoprotein E (APOE), one of the primary lipoproteins in the brain has three isoforms in
humans, APOE2, APOE3, and APOE4. APOE4 is the most well-established risk factor …
humans, APOE2, APOE3, and APOE4. APOE4 is the most well-established risk factor …
[HTML][HTML] NMDAR mediated dynamic changes in m6A inversely correlates with neuronal translation
…, B Nawalpuri, S Ramakrishna, V Jhaveri… - Scientific Reports, 2022 - nature.com
Epitranscriptome modifications are crucial in translation regulation and essential for maintaining
cellular homeostasis. N6 methyladenosine (m 6 A) is one of the most abundant and well-…
cellular homeostasis. N6 methyladenosine (m 6 A) is one of the most abundant and well-…
Function of FMRP domains in regulating distinct roles of neuronal protein synthesis
…, S Ramakrishna, BK Radhakrishna, V Jhaveri… - Molecular …, 2022 - Springer
The Fragile-X Mental Retardation Protein (FMRP) is an RNA binding protein that regulates
translation of mRNAs essential for synaptic development and plasticity. FMRP interacts with a …
translation of mRNAs essential for synaptic development and plasticity. FMRP interacts with a …
[PDF][PDF] The synaptic and neurobiological role of apolipoprotein E4 in models of Alzheimer's disease
S Konings - 2022 - portal.research.lu.se
Alzheimer’s disease (AD) is a progressive, age-related neurodegenerative disorder that is
clinically characterized by memory problems. On a neuropathological level, AD is …
clinically characterized by memory problems. On a neuropathological level, AD is …
Role of schizophrenia-associated transcription factor Tcf4 in mature neurons
D Sarkar - 2023 - tdudspace.texicon.in
The dendritic arbor of neurons is responsible for its circuit integration and is thought to be a
largely stable structure in the adult brain, as opposed to the highly dynamic spines of the …
largely stable structure in the adult brain, as opposed to the highly dynamic spines of the …