Informatics for Integrating Biology and the Bedside (i2b2) is one of seven projects sponsored
by the NIH Roadmap National Centers for Biomedical Computing ( http://www.ncbcs.org ). …

Objective To quantify the impact of citalopram and other selective serotonin reuptake inhibitors
on corrected QT interval (QTc), a marker of risk for ventricular arrhythmia, in a large and …

Objective Electronic medical records (EMRs) are a rich data source for discovery research
but are underutilized due to the difficulty of extracting highly accurate clinical data. We …

Electronic medical records are emerging as a major source of data for clinical and translational
research studies, although phenotypes of interest need to be accurately defined first. This …

Background Vitamin D may have an immunologic role in Crohn’s disease (CD) and ulcerative
colitis (UC). Retrospective studies suggested a weak association between vitamin D …

Objectives Electronic health records (EHR) can allow for the generation of large cohorts of
individuals with given diseases for clinical and genomic research. A rate-limiting step is the …

Informatics for Integrating Biology and the Bedside (i2b2) is one of the sponsored initiatives
of the NIH Roadmap National Centers for Biomedical Computing (http://www. bisti. nih. gov/…

Background Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic and
environmental risk factors that disproportionately afflicts communities of color. Leveraging …

Background Previous studies identifying patients with inflammatory bowel disease using
administrative codes have yielded inconsistent results. Our objective was to develop a robust …

Objective Analysis of narrative (text) data from electronic health records (EHRs) can improve
population-scale phenotyping for clinical and genetic research. Currently, selection of text …