Bacterial proteins pinpoint a single eukaryotic root

R Derelle, G Torruella, V Klimeš… - Proceedings of the …, 2015 - National Acad Sciences
The large phylogenetic distance separating eukaryotic genes and their archaeal orthologs
has prevented identification of the position of the eukaryotic root in phylogenomic studies. …

[HTML][HTML] Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis

E Gentekaki, BA Curtis, CW Stairs, V Klimeš… - PLoS …, 2017 - journals.plos.org
Blastocystis is the most prevalent eukaryotic microbe colonizing the human gut, infecting
approximately 1 billion individuals worldwide. Although Blastocystis has been linked to …

[HTML][HTML] Updating algal evolutionary relationships through plastid genome sequencing: did alveolate plastids emerge through endosymbiosis of an ochrophyte?

T Ševčíková, A Horák, V Klimeš, V Zbránková… - Scientific reports, 2015 - nature.com
Algae with secondary plastids of a red algal origin, such as ochrophytes (photosynthetic
stramenopiles), are diverse and ecologically important, yet their evolutionary history remains …

[HTML][HTML] The draft nuclear genome sequence and predicted mitochondrial proteome of Andalucia godoyi, a protist with the most gene-rich and bacteria-like …

MW Gray, G Burger, R Derelle, V Klimeš, MM Leger… - BMC biology, 2020 - Springer
Background Comparative analyses have indicated that the mitochondrion of the last
eukaryotic common ancestor likely possessed all the key core structures and functions that are …

A gene transfer event suggests a long-term partnership between eustigmatophyte algae and a novel lineage of endosymbiotic bacteria

…, T Ševčíková, P Přibyl, K El Karkouri, V Klimeš… - The ISME …, 2018 - academic.oup.com
Rickettsiales are obligate intracellular bacteria originally found in metazoans, but more recently
recognized as widespread endosymbionts of various protists. One genus was detected …

[HTML][HTML] Peculiar features of the plastids of the colourless alga Euglena longa and photosynthetic euglenophytes unveiled by transcriptome analyses

…, Z Füssy, E Birčák, AMG Novák Vanclová, V Klimeš… - Scientific Reports, 2018 - nature.com
Euglenophytes are a familiar algal group with green alga-derived secondary plastids, but
the knowledge of euglenophyte plastid function and evolution is still highly incomplete. With …

Rho GTPases: deciphering the evolutionary history of a complex protein family

M Eliáš, V Klimeš - Rho GTPases: Methods and Protocols, 2012 - Springer
Rho GTPases constitute a significant subgroup of the eukaryotic Ras superfamily of small
GTPases implicated in the regulation of diverse cellular processes, such as the dynamics of …

The Mastigamoeba balamuthi Genome and the Nature of the Free-Living Ancestor of Entamoeba

V Žárský, V Klimeš, J Pačes, Č Vlček… - Molecular biology …, 2021 - academic.oup.com
The transition of free-living organisms to parasitic organisms is a mysterious process that
occurs in all major eukaryotic lineages. Parasites display seemingly unique features …

[HTML][HTML] Nuclear genetic codes with a different meaning of the UAG and the UAA codon

T Pánek, D Žihala, M Sokol, R Derelle, V Klimeš… - BMC biology, 2017 - Springer
Background Departures from the standard genetic code in eukaryotic nuclear genomes are
known for only a handful of lineages and only a few genetic code variants seem to exist …

A comparative analysis of mitochondrial genomes in eustigmatophyte algae

T Ševčíková, V Klimeš, V Zbránková… - Genome biology and …, 2016 - academic.oup.com
Eustigmatophyceae (Ochrophyta, Stramenopiles) is a small algal group with species of the
genus Nannochloropsis being its best studied representatives. Nuclear and organellar …