From nonpeptide toward noncarbon protease inhibitors: metallacarboranes as specific and potent inhibitors of HIV protease

…, J Bodem, HG Kräusslich, V Král… - Proceedings of the …, 2005 - National Acad Sciences
HIV protease (PR) represents a prime target for rational drug design, and protease inhibitors
(PI) are powerful antiviral drugs. Most of the current PIs are pseudopeptide compounds with …

Application of gold nanoparticles in separation sciences

…, P Řezanka, K Záruba, P Matějka, V Král - Journal of separation …, 2010 - Wiley Online Library
The review article is devoted mainly to the description of applications of gold nanoparticles (GNPs)
in separation sciences, especially in electromigration and chromatographic …

Application of cyclodextrins in chiral capillary electrophoresis

P Řezanka, K Navrátilová, M Řezanka, V Král… - …, 2014 - Wiley Online Library
CE represents a very powerful separation tool in the area of chiral separations. CD‐mediated
chiral CE is a continuously flourishing technique within the frame of the electromigration …

Calixphyrins. Hybrid macrocycles at the structural crossroads between porphyrins and calixpyrroles

…, RS Zimmerman, C Bucher, V Král… - Pure and applied …, 2001 - degruyter.com
Calixphyrins are a class of hybrid molecules that lie at the structural crossroads between
porphyrins and calixpyrroles. Porphyrins, long known for their versatile metal cation …

Porphyrin− cyclodextrin conjugates as a nanosystem for versatile drug delivery and multimodal cancer therapy

…, P Poucková, A Kral, P Martásek, V Král - Journal of medicinal …, 2010 - ACS Publications
The porphyrin−cyclodextrin conjugates were prepared and tested for selective and effective
multifunctional drug delivery and therapy. The porphyrin receptor system combines efficient …

[HTML][HTML] Gold and silver nanoparticles for biomolecule immobilization and enzymatic catalysis

GA Petkova, К Záruba, P Žvátora, V Král - Nanoscale research letters, 2012 - Springer
In this work, a simple method for alcohol synthesis with high enantiomeric purity was proposed.
For this, colloidal gold and silver surface modifications with 3-mercaptopropanoic acid …

Molecular assembly of metallacarboranes in water: Light scattering and microscopy study

P Matějíček, P Cígler, K Procházka, V Král - Langmuir, 2006 - ACS Publications
Polyhedral metallacarboranes are used mainly as ion-pairing agents and recently have
been recognized as potent inhibitors of HIV protease. They are characterized by exceptional …

Recent advances in mixed‐mode chromatographic stationary phases

…, P Řezanka, K Záruba, V Král - Journal of separation …, 2019 - Wiley Online Library
Mixed‐mode phases have become very popular in the last decade, and the number of new
mixed/multi‐mode sorbents is growing fast. Unlike single‐mode stationary phases, perfectly …

Percutaneous treatment of benign bile duct strictures

M Köcher, M Černá, R Havlík, V Král, A Gryga… - European journal of …, 2007 - Elsevier
PURPOSE: To evaluate long-term results of treatment of benign bile duct strictures.
MATERIALS AND METHODS: From February 1994 to November 2005, 21 patients (9 men, 12 …

Identification of intramolecular hydrogen bonds as the origin of malfunctioning of multitopic receptors

B Dolenský, R Konvalinka, M Jakubek, V Král - Journal of molecular …, 2013 - Elsevier
Several trisamides of N,N-bis(2-aminoethyl)ethane-1,2-amine are prepared as potential
saccharide receptors. Surprisingly low or even nil affinity to n-octyl-glucose is found by 1 H NMR …