A novel approach to tailored selective excitation for the measurement of NMR spectra in non-deuterated
aqueous solutions (WATERGATE, WATER suppression by GraAdient-Tailored …

Variants in the FTO (fat mass and obesity associated) gene are associated with increased
body mass index in humans. Here, we show by bioinformatics analysis that FTO shares …

FTO is a nuclear protein belonging to the AlkB-related non-haem iron- and 2-oxoglutarate-dependent
dioxygenase family. Although polymorphisms within the first intron of the FTO gene …

Carnosine (β-alanyl-l-histidine) and homocarnosine (γ-aminobutyric acid-l-histidine) are two
naturally occurring dipeptides with potential neuroprotective and neurotransmitter functions …

The endoplasmic reticulum (ER) stress response detects malfunctions in cellular physiology,
and microbial pattern recognition receptors recognize external threats posed by infectious …

Lipodystrophic syndromes are characterized by adipose tissue deficiency. Although rare, they
are of considerable interest as they, like obesity, typically lead to ectopic lipid accumulation…

GDF15 has recently gained scientific and translational prominence with the discovery that its
receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain…

Phosphatidylcholine (PC) is the major glycerophospholipid in eukaryotic cells and is an
essential component in all cellular membranes. The biochemistry of de novo PC synthesis by the …

Perilipins (PLINs) play a key role in energy storage by orchestrating the activity of lipases on
the surface of lipid droplets. Failure of this activity results in severe metabolic disease in …

Structural maintenance of chromosomes (SMC) complexes are essential for maintaining
chromatin structure and regulating gene expression. Two the three known SMC complexes, …