User profiles for Vladimir V. Bezuglov

Vladimir Bezuglov

Shemykin-Ovchinikov Institute of Bioorganic Chemistry RAS
Verified email at ibch.ru
Cited by 2686

N-acyl-dopamines: novel synthetic CB1 cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo

…, MY Bobrov, NM Gretskaya, VV Bezuglov… - Biochemical …, 2000 - portlandpress.com
We reported previously that synthetic amides of polyunsaturated fatty acids with bioactive
amines can result in substances that interact with proteins of the endogenous cannabinoid …

Antioxidant and neuroprotective properties of N-arachidonoyldopamine

…, LE Frumkina, LG Khaspekov, VV Bezuglov - Neuroscience …, 2008 - Elsevier
N-Acyldopamines were recently described as putative endogenous substances in the rat
brain. Among them, N-arachidonoyldopamine (AADA) was characterized as cannabinoid CB1 …

The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence

…, RE Peterson, LA Nikitina, VV Bezuglov… - Neurochemical …, 2005 - Springer
Forty serotonin-related neurochemicals were tested on embryos and larvae of Lytechinus
variegatus and other sea urchin species. Some of these substances (agonists of 5-HT 1 …

An invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvae.

GA Buznikov, LA Nikitina, VV Bezuglov… - Environmental …, 2001 - ehp.niehs.nih.gov
Chlorpyrifos targets mammalian brain development through a combination of effects directed
at cholinergic receptors and intracellular signaling cascades that are involved in cell …

N‐arachidonoyl dopamine inhibits epithelial–mesenchymal transition of breast cancer cells through ERK signaling and decreasing the cellular cholesterol

…, NM Gretskaya, VV Bezuglov… - … of biochemical and …, 2021 - Wiley Online Library
N‐acyl dopamines (NADAs) are bioactive lipids of the endovanilloid family with known
cytotoxicity for the cancer cells; however, the available data on the participation of the …

[HTML][HTML] The Mechanisms of GPR55 Receptor Functional Selectivity during Apoptosis and Proliferation Regulation in Cancer Cells

…, KO Degtyaryova, IE Deyev, VV Bezuglov - International Journal of …, 2023 - mdpi.com
GPR55 is a non-canonical cannabinoid receptor, important for cancer proliferation. Depending
on the ligand, it induces either cell proliferation or death. The objective of the study was to …

Localization of serotonin and its possible role in early embryos of Tritonia diomedea (Mollusca: Nudibranchia)

…, LA Nikitina, EE Voronezhskaya, VV Bezuglov… - Cell and tissue …, 2003 - Springer
A classical neurotransmitter serotonin (5-HT) was detected immunochemically using laser
scanning microscopy at the early stages of Tritonia diomedea development. At the one- to …

[HTML][HTML] Arachidonoylcholine and other unsaturated long-chain acylcholines are endogenous modulators of the acetylcholine signaling system

…, IA Dyachenko, IE Kasheverov, VI Tsetlin, VV Bezuglov - Biomolecules, 2020 - mdpi.com
Cholines acylated with unsaturated fatty acids are a recently discovered family of endogenous
lipids. However, the data on the biological activity of acylcholines remain very limited. We …

Interactions of β‐lactoglobulin with serotonin and arachidonyl serotonin

…, Y Choiset, DA Faizullin, YF Zuev, VV Bezuglov… - …, 2011 - Wiley Online Library
β‐Lactoglobulin (β‐LG) is a lipocalin, which is the major whey protein of cow's milk and the
milk of other mammals. However, it is absent from human milk. The biological function of β‐…

[HTML][HTML] ACTH(6–9)PGP Peptide Protects SH-SY5Y Cells from H2O2, tert-Butyl Hydroperoxide, and Cyanide Cytotoxicity via Stimulation of Proliferation and …

…, LA Andreeva, NF Myasoyedov, VV Bezuglov - Molecules, 2021 - mdpi.com
Stabilized melanocortin analog peptide ACTH(6–9)PGP (HFRWPGP) possesses a wide range
of neuroprotective activities. However, its mechanism of action remains poorly understood…