User profiles for Vladimir V. Bezuglov
Vladimir BezuglovShemykin-Ovchinikov Institute of Bioorganic Chemistry RAS Verified email at ibch.ru Cited by 2686 |
N-acyl-dopamines: novel synthetic CB1 cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo
…, MY Bobrov, NM Gretskaya, VV Bezuglov… - Biochemical …, 2000 - portlandpress.com
We reported previously that synthetic amides of polyunsaturated fatty acids with bioactive
amines can result in substances that interact with proteins of the endogenous cannabinoid …
amines can result in substances that interact with proteins of the endogenous cannabinoid …
Antioxidant and neuroprotective properties of N-arachidonoyldopamine
…, LE Frumkina, LG Khaspekov, VV Bezuglov - Neuroscience …, 2008 - Elsevier
N-Acyldopamines were recently described as putative endogenous substances in the rat
brain. Among them, N-arachidonoyldopamine (AADA) was characterized as cannabinoid CB1 …
brain. Among them, N-arachidonoyldopamine (AADA) was characterized as cannabinoid CB1 …
The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence
…, RE Peterson, LA Nikitina, VV Bezuglov… - Neurochemical …, 2005 - Springer
Forty serotonin-related neurochemicals were tested on embryos and larvae of Lytechinus
variegatus and other sea urchin species. Some of these substances (agonists of 5-HT 1 …
variegatus and other sea urchin species. Some of these substances (agonists of 5-HT 1 …
An invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvae.
GA Buznikov, LA Nikitina, VV Bezuglov… - Environmental …, 2001 - ehp.niehs.nih.gov
Chlorpyrifos targets mammalian brain development through a combination of effects directed
at cholinergic receptors and intracellular signaling cascades that are involved in cell …
at cholinergic receptors and intracellular signaling cascades that are involved in cell …
N‐arachidonoyl dopamine inhibits epithelial–mesenchymal transition of breast cancer cells through ERK signaling and decreasing the cellular cholesterol
…, NM Gretskaya, VV Bezuglov… - … of biochemical and …, 2021 - Wiley Online Library
N‐acyl dopamines (NADAs) are bioactive lipids of the endovanilloid family with known
cytotoxicity for the cancer cells; however, the available data on the participation of the …
cytotoxicity for the cancer cells; however, the available data on the participation of the …
[HTML][HTML] The Mechanisms of GPR55 Receptor Functional Selectivity during Apoptosis and Proliferation Regulation in Cancer Cells
…, KO Degtyaryova, IE Deyev, VV Bezuglov - International Journal of …, 2023 - mdpi.com
GPR55 is a non-canonical cannabinoid receptor, important for cancer proliferation. Depending
on the ligand, it induces either cell proliferation or death. The objective of the study was to …
on the ligand, it induces either cell proliferation or death. The objective of the study was to …
Localization of serotonin and its possible role in early embryos of Tritonia diomedea (Mollusca: Nudibranchia)
…, LA Nikitina, EE Voronezhskaya, VV Bezuglov… - Cell and tissue …, 2003 - Springer
A classical neurotransmitter serotonin (5-HT) was detected immunochemically using laser
scanning microscopy at the early stages of Tritonia diomedea development. At the one- to …
scanning microscopy at the early stages of Tritonia diomedea development. At the one- to …
[HTML][HTML] Arachidonoylcholine and other unsaturated long-chain acylcholines are endogenous modulators of the acetylcholine signaling system
…, IA Dyachenko, IE Kasheverov, VI Tsetlin, VV Bezuglov - Biomolecules, 2020 - mdpi.com
Cholines acylated with unsaturated fatty acids are a recently discovered family of endogenous
lipids. However, the data on the biological activity of acylcholines remain very limited. We …
lipids. However, the data on the biological activity of acylcholines remain very limited. We …
Interactions of β‐lactoglobulin with serotonin and arachidonyl serotonin
…, Y Choiset, DA Faizullin, YF Zuev, VV Bezuglov… - …, 2011 - Wiley Online Library
β‐Lactoglobulin (β‐LG) is a lipocalin, which is the major whey protein of cow's milk and the
milk of other mammals. However, it is absent from human milk. The biological function of β‐…
milk of other mammals. However, it is absent from human milk. The biological function of β‐…
[HTML][HTML] ACTH(6–9)PGP Peptide Protects SH-SY5Y Cells from H2O2, tert-Butyl Hydroperoxide, and Cyanide Cytotoxicity via Stimulation of Proliferation and …
…, LA Andreeva, NF Myasoyedov, VV Bezuglov - Molecules, 2021 - mdpi.com
Stabilized melanocortin analog peptide ACTH(6–9)PGP (HFRWPGP) possesses a wide range
of neuroprotective activities. However, its mechanism of action remains poorly understood…
of neuroprotective activities. However, its mechanism of action remains poorly understood…