Technical variation in metagenomic analysis must be minimized to confidently assess the
contributions of microbiota to human health. Here we tested 21 representative DNA extraction …

Intestinal luminal microbiota likely contribute to the etiology of necrotizing enterocolitis (NEC),
a common disease in preterm infants. Microbiota development, a cascade of initial …

The herbicide glyphosate, N-(phosphonomethyl) glycine, has been used extensively in the
past 40 years, under the assumption that side effects were minimal. However, in recent years, …

Background Necrotizing enterocolitis (NEC) is a catastrophic disease of preterm infants,
and microbial dysbiosis has been implicated in its pathogenesis. Studies evaluating the …

Clostridium difficile infection (CDI) causes nearly half a million cases of diarrhea and colitis
in the United States each year. Although the importance of the gut microbiota in C. difficile …

OBJECTIVES: To use high throughput techniques to analyze intestinal microbial ecology in
premature neonates, who are highly susceptible to perturbations of the luminal environment …

Bacteria associated with the onset of type 1 diabetes in a rat model system were identified.
In two experiments, stool samples were collected at three time points after birth from bio-…

Background Diarrheal diseases continue to contribute significantly to morbidity and mortality
in infants and young children in developing countries. There is an urgent need to better …

Background . Diarrhea remains a common complaint among US patients who seek medical
attention. Methods . We performed a prospective study to determine the etiology of diarrheal …

Late onset sepsis (LOS) is a major contributor to neonatal morbidity and mortality, especially
in premature infants. Distortions in the establishment of normal gut microbiota, commensal …