Background Heightened surveillance of acute febrile illness in China since 2009 has led to
the identification of a severe fever with thrombocytopenia syndrome (SFTS) with an unknown …

PURPOSE: Optoacoustic tomography (OAT) is a novel medical imaging method that uses
optical illumination and ultrasonic detection to produce deep tissue images based on their …

Background: Extracellular vesicles contain biological molecules specified by cell-type of
origin and modified by microenvironmental changes. To conduct reproducible studies on …

Tick-borne encephalitis virus (TBEV) (family Flaviviridae, genus Flavivirus) accounts for
approximately 10,000 annual cases of severe encephalitis in Europe and Asia. Here, we …

Epac belongs to a new family of proteins that can directly mediate the action of the intracellular
second messenger cAMP by activating a downstream small GTPase Rap1. The Epac/…

Orientia tsutsugamushi is the etiologic agent of scrub typhus, a chigger-borne zoonosis that
is a highly prevalent, life-threatening illness of greatest public health importance in tropical …

Many viruses have evolved mechanisms to alter mitochondrial function. The hepatitis C
virus (HCV) produces a viral core protein that targets to mitochondria and increases Ca 2+ ‐…

Most alphaviruses and many other arboviruses are mosquito-borne and exhibit a broad host
range, infecting many different vertebrates including birds, rodents, equids, humans, and …

Human lung epithelial cells are likely among the first targets to encounter invading severe
acute respiratory syndrome-associated coronavirus (SARS-CoV). Not only can these cells …

In this study, we delineated the role of N-acylhomoserine lactone(s) (AHLs)-mediated
quorum sensing (QS) in the virulence of diarrhoeal isolate SSU of Aeromonas hydrophila by …