Comparative assessments of CRISPR-Cas nucleases' cleavage efficiency in planta

RA Johnson, V Gurevich, S Filler, A Samach… - Plant molecular …, 2015 - Springer
Custom-designed nucleases can enable precise plant genome editing by catalyzing DNA-breakage
at specific targets to stimulate targeted mutagenesis or gene replacement. The …

[PDF][PDF] Genetic variation in date palms propagated from offshoots and tissue culture

V Gurevich, U Lavi, Y Cohen - Journal of the American Society for …, 2005 - journals.ashs.org
Date palm (Phoenix dactylifera L.) is a major tree crop in arid regions of the Middle East and
North Africa, having an important impact on the economy of many countries in these regions…

[HTML][HTML] L-Norvaline, a new therapeutic agent against Alzheimer's disease

B Polis, KD Srikanth, V Gurevich… - Neural regeneration …, 2019 - journals.lww.com
Growing evidence highlights the role of arginase activity in the manifestation of Alzheimer’s
disease (AD). Upregulation of arginase was shown to contribute to neurodegeneration. …

Effects of chronic arginase inhibition with Norvaline on tau pathology and brain glucose metabolism in Alzheimer's disease mice

B Polis, M Squillario, V Gurevich, KD Srikanth… - Neurochemical …, 2022 - Springer
Alzheimer's disease (AD) is an insidious neurodegenerative disorder representing a serious
continuously escalating medico-social problem. The AD-associated progressive dementia …

[HTML][HTML] Norvaline restores the BBB integrity in a mouse model of Alzheimer's disease

B Polis, V Gurevich, M Assa, AO Samson - International journal of …, 2019 - mdpi.com
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder and the leading cause of
dementia. The disease progression is associated with the build-up of amyloid plaques and …

[HTML][HTML] Arginase inhibition supports survival and differentiation of neuronal precursors in adult Alzheimer's disease mice

B Polis, KD Srikanth, V Gurevich, N Bloch… - International Journal of …, 2020 - mdpi.com
Adult neurogenesis is a complex physiological process, which plays a central role in maintaining
cognitive functions, and consists of progenitor cell proliferation, newborn cell migration, …

Heat capacity and thermodynamic properties of lanthanum orthoniobate

…, A Khoroshilov, A Tyurin, V Gurevich… - The Journal of Chemical …, 2019 - Elsevier
Temperature dependences of the heat capacity and the enthalpy change of LaNbO 4 were
measured using various calorimetric methods (adiabatic, differential scanning and drop …

Faithful modeling of transient expression and its application to elucidating negative feedback regulation

A Rubinstein, V Gurevich… - Proceedings of the …, 2007 - National Acad Sciences
Modeling and analysis of genetic regulatory networks is essential both for better understanding
their dynamic behavior and for elucidating and refining open issues. We hereby present …

A rapid assay to quantify the cleavage efficiency of custom-designed nucleases in planta

RA Johnson, V Gurevich, AA Levy - Plant molecular biology, 2013 - Springer
Custom-designed nucleases are a promising technology for genome editing through the
catalysis of double-strand DNA breaks within target loci and subsequent repair by the host cell, …

[HTML][HTML] A switch from a gradient to a threshold mode in the regulation of a transcriptional cascade promotes robust execution of meiosis in budding yeast

V Gurevich, Y Kassir - PloS one, 2010 - journals.plos.org
Tight regulation of developmental pathways is of critical importance to all organisms, and is
achieved by a transcriptional cascade ensuring the coordinated expression of sets of genes. …