Genome-wide association studies (GWAS) have evolved over the last ten years into a powerful
tool for investigating the genetic architecture of human disease. In this work, we review …

Acute, potentially life-threatening systemic reactions to contrast media are less frequent with
lower osmolality, nonionic contrast agents, but they are not totally eliminated. Severe …

Advances in genotyping technology have, over the past decade, enabled the focused search
for common genetic variation associated with human diseases and traits. With the recently …

Abstract Characterization of the genetic landscape of Alzheimer’s disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

Risk for late-onset Alzheimer’s disease (LOAD), the most prevalent dementia, is partially
driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association …

There are important classes of programming errors that are hard to diagnose, both manually
and automatically, because they involve a program's dynamic behavior. This article …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

Multifactor dimensionality reduction (MDR) was developed as a method for detecting statistical
patterns of epistasis. The overall goal of MDR is to change the representation space of …

Many modern human genomes retain DNA inherited from interbreeding with archaic
hominins, such as Neandertals, yet the influence of this admixture on human traits is largely …

Retroperitoneal masses not arising from major solid organs are uncommon. Although there
is no simple method of classifying retroperitoneal masses, a reasonable approach is to …