1, 5-Anhydroglucitol in saliva is a noninvasive marker of short-term glycemic control

…, S Abdul Kader, WA Al Muftah… - The Journal of …, 2014 - academic.oup.com
Context: Randomized controlled trials (RCTs) investigating the efficacy of vitamin D (Vit D)
in depression provided inconsistent results. Objective: We aim to summarize the evidence of …

[HTML][HTML] Epigenetic associations of type 2 diabetes and BMI in an Arab population

WA Al Muftah, M Al-Shafai, SB Zaghlool, A Visconti… - Clinical …, 2016 - Springer
Background The prevalence of type 2 diabetes (T2D) and obesity has dramatically increased
within a few generations, reaching epidemic levels. In addition to genetic risk factors, …

[HTML][HTML] Association of DNA methylation with age, gender, and smoking in an Arab population

SB Zaghlool, M Al-Shafai, WA Al Muftah, P Kumar… - Clinical …, 2015 - Springer
Background Modification of DNA by methylation of cytosines at CpG dinucleotides is a
widespread phenomenon that leads to changes in gene expression, thereby influencing and …

[HTML][HTML] A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control

…, J Rowe, OM Chidiac, C McKeon, WA Al Muftah… - Diabetologia, 2015 - Springer
Aims/hypothesis Metabolomics has opened new avenues for studying metabolic alterations
in type 2 diabetes. While many urine and blood metabolites have been associated …

Ethnic and gender differences in advanced glycation end products measured by skin auto-fluorescence

…, OM Chidiac, SA Kader, WA Al Muftah… - Dermato …, 2013 - Taylor & Francis
Background Advanced glycation end products (AGEs) have been shown to be a predictor of
cardiovascular risk in Caucasian subjects. In this study we examine whether the existing …

[HTML][HTML] Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects

SB Zaghlool, M Al-Shafai, WA Al Muftah, P Kumar… - Clinical …, 2016 - Springer
Background Environmentally influenced phenotypes, such as obesity and insulin resistance,
can be transmitted over multiple generations. Epigenetic modifications, such as methylation …

[HTML][HTML] Evaluation of SNP calling using single and multiple-sample calling algorithms by validation against array base genotyping and Mendelian inheritance

P Kumar, M Al-Shafai, WA Al Muftah, N Chalhoub… - BMC Research …, 2014 - Springer
Background With diminishing costs of next generation sequencing (NGS), whole genome
analysis becomes a standard tool for identifying genetic causes of inherited diseases. …

[HTML][HTML] PopPAnTe: population and pedigree association testing for quantitative data

A Visconti, M Al-Shafai, WA Al Muftah, SB Zaghlool… - BMC genomics, 2017 - Springer
Background Family-based designs, from twin studies to isolated populations with their
complex genealogical data, are a valuable resource for genetic studies of heritable molecular …

[HTML][HTML] Elevated HbA1c levels in individuals not diagnosed with type 2 diabetes in Qatar: a pilot study

…, H Al-Homsi, C McKeon, WA Al Muftah… - Qatar Medical …, 2015 - qscience.com
Background: The prevalence of type 2 diabetes (T2D) in Qatar and the Middle East is one of
the highest in the world. It is estimated that about one quarter of the individuals with T2D are …

[PDF][PDF] Ethnic and gender diferences in advanced glycation end products measured by skin auto-luorescence

WA Al Muftah, C McKeon, K Suhre… - academia.edu
Background: Advanced glycation end products (AGEs) have been shown to be a predictor
of cardiovascular risk in Caucasian subjects. In this study we examine whether the existing …