Determination of macromolecular structures from anomalous diffraction of synchrotron radiation

WA Hendrickson - Science, 1991 - science.org
Resonance between beams of x-ray waves and electronic transitions from bound atomic
orbitals leads to a phenomenon known as anomalous scattering. This effect can be exploited in …

Sensor domains of two-component regulatory systems

J Cheung, WA Hendrickson - Current opinion in microbiology, 2010 - Elsevier
… HK1 s -Z6 (Zhang and Hendrickson, submitted) reveals a dimeric association between
membrane-distal regions of the N-terminal helices, such that the helical N-terminal and C-…

Stereochemically restrained refinement of macromolecular structures

WA Hendrickson - Methods in enzymology, 1985 - Elsevier
… 4 WA Hendrickson and JH Konnert, in "Biomolecular Structure, Function, Conformation and
… 5 WA Hendrickson, in "Refinement of Protein Structures" (PA Machin, JW Campbell, and M. …

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

…, J Robinson, RW Sweet, J Sodroski, WA Hendrickson - Nature, 1998 - nature.com
The entry of human immunodeficiency virus (HIV) into cells requires the sequential
interaction of the viral exterior envelope glycoprotein, gp120, with the CD4 glycoprotein and a …

Anomalous diffraction in crystallographic phase evaluation

WA Hendrickson - Quarterly reviews of biophysics, 2014 - cambridge.org
… Anomalous scattering information was also shown to suffice on its own for phase evaluation
in the solution of the structure of crambin (Hendrickson & Teeter, 1981), which we now see …

Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three‐dimensional structure.

WA Hendrickson, JR Horton, DM LeMaster - The EMBO journal, 1990 - embopress.org
… selenolanthionine (Hendrickson, 1985) and of selenobiotinyl streptavidin (Hendrickson et
al.… diffraction data involves a leastsquares optimization (Hendrickson, 1985) based on an exact …

[HTML][HTML] The antigenic structure of the HIV gp120 envelope glycoprotein

…, RW Sweet, J Robinson, WA Hendrickson… - Nature, 1998 - nature.com
The human immunodeficiency virus HIV-1 establishes persistent infections in humans which
lead to acquired immunodeficiency syndrome (AIDS). The HIV-1 envelope glycoproteins, …

Structural analysis of substrate binding by the molecular chaperone DnaK

…, CM Ogata, ME Gottesman, WA Hendrickson - Science, 1996 - science.org
… Gragerov, ME Gottesman, and WA Hendrickson are in the Department of Biochemistry and
Molecular Biophysics, College of Physicians and Surgeons, Columbia University, New York, …

Structural basis of cell-cell adhesion by cadherins

…, J Als-Nielsen, DR Colman, WA Hendrickson - Nature, 1995 - nature.com
Crystal structures of the amino-terminal domain of N-cadherin provide a picture at the atomic
level of a specific adhesive contact between cells. A repeated set of dimer interfaces is …

Crystal structure of the tyrosine kinase domain of the human insulin receptor

SR Hubbard, L Wei, WA Hendrickson - Nature, 1994 - nature.com
The X-ray crystal structure of the tyrosine kinase domain of the human insulin receptor has
been determined by multiwavelength anomalous diffraction phasing and refined to 2.1 Å …