Epileptic encephalopathies (EEs) are the most clinically important group of severe early-onset
epilepsies. Next-generation sequencing has highlighted the crucial contribution of de …

Sequencing-based studies have identified novel risk genes associated with severe epilepsies
and revealed an excess of rare deleterious variation in less-severe forms of epilepsy. To …

Background Despite progress in understanding the genetics of rare epilepsies, the more
common epilepsies have proven less amenable to traditional gene-discovery analyses. We …

Policy makers, clinicians, and patients increasingly recognize the need for greater patient
involvement in clinical decision-making. Shared decision-making helps address these …

Objective To characterize trends in incidence, prevalence, and health care outcomes in the
idiopathic intracranial hypertension (IIH) population in Wales using routinely collected health …

The World Health Organization (WHO) has recently announced its plan to eliminate Human
African trypanosomiasis (HAT). The plan’s main focus is on the Trypanosoma brucei …

Objective This study was undertaken to determine whether epilepsy and antiepileptic drugs (including
enzyme‐inducing and non‐enzyme‐inducing drugs) are associated with major …

Objective To investigate whether the link between epilepsy and deprivation is due to factors
associated with deprivation (social causation) or factors associated with a diagnosis of …

Sudden unexpected death in epilepsy (SUDEP) represents the most severe degree of the
spectrum of epilepsy severity and is the commonest cause of epilepsy-related premature …

Aim To investigate antiepileptic drug (AED)-related weight changes in patients with epilepsy
through a retrospective observational study. Method We analysed the anonymised …