User profiles for W. R. Jeffery

William Richard Jeffery

Distinguished University Professor
Verified email at umd.edu
Cited by 12800

Cavefish as a model system in evolutionary developmental biology

WR Jeffery - Developmental biology, 2001 - Elsevier
… evolutionary developmental biology in invertebrates (Jeffery and Swalla, 1992; Raff, 1992; …
no differences in the structure of individual taste buds in surface fish and cavefish (Jeffery et …

Regressive Evolution in Astyanax Cavefish

WR Jeffery - Annual review of genetics, 2009 - annualreviews.org
… Yamamoto and WR Jeffery, unpublished). Recent studies have shown that crosses between
different cavefish populations can rescue vision, restoring sight to cavefish lineages that …

Adaptive evolution of eye degeneration in the Mexican blind cavefish

WR Jeffery - Journal of Heredity, 2005 - academic.oup.com
Jeffery unpublished data). Second, large numbers of transcripts have been directly compared
between surface fish and cavefish embryos by microarray analysis (Strickler and Jeffery

Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism

…, D Kochanek, Y Zhou, H Wilkens, WR Jeffery… - Nature …, 2006 - nature.com
The genetic basis of vertebrate morphological evolution has traditionally been very difficult
to examine in naturally occurring populations. Here we describe the generation of a genome-…

Cryptic variation in morphological evolution: HSP90 as a capacitor for loss of eyes in cavefish

…, DF Jarosz, JE Kowalko, M Yoshizawa, WR Jeffery… - Science, 2013 - science.org
In the process of morphological evolution, the extent to which cryptic, preexisting variation
provides a substrate for natural selection has been controversial. We provide evidence that …

Central role for the lens in cave fish eye degeneration

Y Yamamoto, WR Jeffery - Science, 2000 - science.org
Astyanax mexicanus is a teleost with eyed surface-dwelling and eyeless cave-dwelling
forms. Eye formation is initiated in cave fish embryos, but the eye subsequently arrests and …

Hedgehog signalling controls eye degeneration in blind cavefish

Y Yamamoto, DW Stock, WR Jeffery - Nature, 2004 - nature.com
Hedgehog (Hh) proteins are responsible for critical signalling events during development 1
but their evolutionary roles remain to be determined. Here we show that hh gene expression …

[HTML][HTML] The cavefish genome reveals candidate genes for eye loss

…, R Borowsky, D Chalopin, H Hinaux, WR Jeffery… - Nature …, 2014 - nature.com
… Source DNA was obtained from the Jeffery Lab. DNA was collected from heart, liver, spleen
… Samples for genome annotation were taken in the Jeffery lab under animal care protocols …

[PDF][PDF] Evolution of a behavioral shift mediated by superficial neuromasts helps cavefish find food in darkness

M Yoshizawa, Š Gorički, D Soares, WR Jeffery - Current biology, 2010 - cell.com
How cave animals adapt to life in darkness is a poorly understood aspect of evolutionary
biology [1]. Here we identify a behavioral shift and its morphological basis in Astyanax …

Localization of actin messenger RNA during early ascidian development

WR Jeffery, CR Tomlinson, RD Brodeur - Developmental biology, 1983 - Elsevier
… Eggs and developing embryos were fixed at -20C for 30 min in modified Petrunkewitsch’s
fluid, a fixative which quantitatively retains RNA in the specimens (Jeffery, unpublished) and …