… where the weight function w is a normalized form of the … 76 1346 [4] Nonner W and Eisenberg
B 1998 Biophys. J. 75 … 3 1644 [14] Nonner W, Gillespie D, Henderson D and Eisenberg B …

… Wolfgang Nonner has constructed a mean field model of single filing, by extending PNP
to include convection. This Navier-Stokes extension of PNP is clearly able to predict the …

L-type Ca channels contain a cluster of four charged glutamate residues (EEEE locus), which
seem essential for high Ca specificity. To understand how this highly charged structure …

L-type calcium channels are Ca 2+ binding proteins of great biological importance. They
generate an essential intracellular signal of living cells by allowing Ca 2+ ions to move across …

An approximate electrostatic (ES) excess free energy functional for charged, hard sphere
fluids is presented. This functional is designed for systems with large density variations, but …

… The probability of accepting a trial move in the canonical ensemble is min1,exp(W/kT), where
k is Boltzmann’s constant and W is the energy change of the move, the quantity we need to …

Monte Carlo simulations of equilibrium selectivity of Na channels with a DEKA locus are
performed over a range of radius R and protein dielectric coefficient ɛ p . Selectivity arises from …

Ionic channels bathed in mixed solutions of two permeant electrolytes often conduct less
current than channels bathed in pure solutions of either. For many years, this anomalous mole …

Calcium-selective ion channels are known to have carboxylate-rich selectivity filters, a
common motif that is primarily responsible for their high Ca 2+ affinity. Different Ca 2+ affinities …

We suggest that bubbles are the bistable hydrophobic gates responsible for the on-off
transitions of single channel currents. In this view, many types of channels gate by the same …