Closed‐loop adaptive deep brain stimulation (aDBS) can deliver individualized therapy at an
unprecedented temporal precision for neurological disorders. This has the potential to lead …

Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …

Deep brain stimulation (DBS) surgery offers a unique opportunity to record local field
potentials (LFPs), the electrophysiological population activity of neurons surrounding the depth …

Deep brain stimulation (DBS) is a highly efficacious treatment option for movement disorders
and a growing number of other indications are investigated in clinical trials. To ensure …

Objective Beta band oscillations in the subthalamic nucleus (STN) have been proposed as
a pathophysiological signature in patients with Parkinson's disease (PD). The aim of this …

… STN beta power off medication correlates with motor impairment in PD [Neumann et al., 2016;
… signal processing procedures are described in detail elsewhere [Neumann et al., 2015a, …

Parkinson’s disease (PD) is characterised by the emergence of beta frequency oscillatory
synchronisation across the cortico-basal-ganglia circuit. The relationship between the …

Deep brain stimulation of the globus pallidus internus alleviates involuntary movements in
patients with dystonia. However, the mechanism is still not entirely understood. One …

Objectives To investigate the long term association of subthalamic beta activity with parkinsonian
motor signs. Methods We recruited 15 patients with Parkinson’s disease undergoing …

Primary dystonia has been associated with an underlying dysfunction of a wide network of
brain regions including the motor cortex, basal ganglia, cerebellum, brainstem and spinal cord…