[HTML][HTML] Whitefly genomes contain ribotoxin coding genes acquired from plants

WJ Lapadula, ML Mascotti, M Juri Ayub - Scientific Reports, 2020 - nature.com
Ribosome inactivating proteins (RIPs) are RNA N-glycosidases that depurinate a specific
adenine residue in the conserved sarcin/ricin loop of 28S rRNA. These enzymes are widely …

[HTML][HTML] Revising the taxonomic distribution, origin and evolution of ribosome inactivating protein genes

WJ Lapadula, MV Sanchez Puerta, M Juri Ayub - PloS one, 2013 - journals.plos.org
Ribosome inactivating proteins are enzymes that depurinate a specific adenine residue in
the alpha-sarcin-ricin loop of the large ribosomal RNA, being ricin and Shiga toxins the most …

Ribosome inactivating proteins in insects: HGT, gene expression, and functional implications

WJ Lapadula, MJ Ayub - Gene, 2023 - Elsevier
Ribosome-inactivating proteins (RIPs) are RNA N-glycosidases that depurinate an adenine
residue in the conserved alpha-sarcin/ricin loop (SRL) of rRNA, inhibiting protein synthesis. …

[HTML][HTML] Metazoan ribosome inactivating protein encoding genes acquired by horizontal gene transfer

WJ Lapadula, PL Marcet, ML Mascotti… - Scientific Reports, 2017 - nature.com
Ribosome inactivating proteins (RIPs) are RNA N-glycosidases that depurinate a specific
adenine residue in the conserved sarcin/ricin loop of 28S rRNA. These enzymes are widely …

Convergent evolution led ribosome inactivating proteins to interact with ribosomal stalk

WJ Lapadula, MV Sanchez-Puerta, MJ Ayub - Toxicon, 2012 - Elsevier
Ribosome-inactivating proteins (RIPs) inhibit protein synthesis by depurinating an adenine
on the sarcin–ricin loop (SRL) of the large subunit ribosomal RNA. Several RIPs interact with …

[HTML][HTML] Characterization of Novel Trypanosoma cruzi-Specific Antigen with Potential Use in the Diagnosis of Chagas Disease

…, LL Niborski, J Rodríguez-Durán, WJ Lapadula… - International Journal of …, 2024 - mdpi.com
Chagas disease is caused by the parasite Trypanosoma cruzi. In humans, it evolves into a
chronic disease, eventually resulting in cardiac, digestive, and/or neurological disorders. In …

Characterization of horizontally acquired ribotoxin encoding genes and their transcripts in Aedes aegypti

WJ Lapadula, PL Marcet, ML Taracena, A Lenhart… - Gene, 2020 - Elsevier
Ribosome Inactivating Proteins (RIPs) are RNA N-glycosidases that depurinate a specific
adenine residue in the conserved sarcin/ricin loop of the 28S rRNA. The occurrence of RIP …

[PDF][PDF] Ribosomes from Trypanosomatids: unique structural and functional properties

MJ Ayub, WJ Lapadula, J Hoebeke… - Cell-Free Protein …, 2012 - library2.um.edu.mo

Recurrent acquisition of alien ribotoxin encoding genes by insect genomes

WJ Lapadula, ML Mascotti, MJ Ayub - bioRxiv, 2019 - biorxiv.org
Ribosome inactivating proteins (RIPs) are RNA N-glycosidases that depurinate a specific
adenine residue in the conserved sarcin/ricin loop of 28S rRNA. These enzymes are widely …

Foreign Ribosome Inactivating Proteins as immune effectors in insects

WJ Lapadula, MJ Ayub - bioRxiv, 2023 - biorxiv.org
Ribosome inactivating proteins (RIPs) are RNA N-glycosidases that depurinate an adenine
residue in the conserved alpha-sarcin/ricin loop (SRL) of rRNA. This ribosomal modification …