We have compiled a comprehensive QST protocol as part of the German Research Network
on Neuropathic Pain (DFNS) using well established tests for nearly all aspects of …

Clinical use of quantitative sensory testing (QST) requires standardization. The German
research network on neuropathic pain (DFNS) solves this problem by defining reference data …

Patients with neuropathic pain are heterogeneous in etiology, pathophysiology, and clinical
appearance. They exhibit a variety of painrelated sensory symptoms and signs (sensory …

Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength are
ubiquitous mechanisms of synaptic plasticity, but their functional relevance in humans remains …

Polymodal nociceptors respond to mechanical, thermal and chemical stimuli. Whereas
sensitivities to heat and to the irritant substance capsaicin have recently been linked via the …

Objective. Deep and slow breathing (DSB) techniques, as a component of various relaxation
techniques, have been reported as complementary approaches in the treatment of chronic …

Wind-up and secondary hyperalgesia both are related to central sensitization, but whereas
the former is explained by homosynaptic facilitation, the latter is due to heterosynaptic …

Sleep disturbances are highly prevalent in chronic pain patients. Understanding their
relationship has become an important research topic since poor sleep and pain are assumed to …

Patients with sensory disturbances of painful and non-painful character show distinct changes
in touch and/or pain sensitivity. The patterns of sensory changes were compared to those …

Although patients with a depressive disorder report often of pain, their sensitivity to experimental
pain is controversial, probably due to differences in sensory testing methods and to the …