[HTML][HTML] Biological and historical overview of Zika virus

N Armstrong, W Hou, Q Tang - World journal of virology, 2017 - ncbi.nlm.nih.gov
The recent outbreak of the Zika virus attracts worldwide attention probably because the most
recently affected country (Brazil) will host the 2016 Olympic Game. Zika virus infected cases …

[HTML][HTML] The prevalence of antibodies to SARS-CoV-2 among blood donors in China

L Chang, W Hou, L Zhao, Y Zhang, Y Wang… - Nature …, 2021 - nature.com
In this study, we investigate the seroprevalence of SARS-CoV-2 antibodies among blood
donors in the cities of Wuhan, Shenzhen, and Shijiazhuang in China. From January to April …

Molecular cloning and characterization of the genes encoding the proteins of Zika virus

W Hou, R Cruz-Cosme, N Armstrong, LA Obwolo… - Gene, 2017 - Elsevier
Zika virus (ZIKV) encodes a precursor protein (also called polyprotein) of about 3424 amino
acids that is processed by proteases to generate 10 mature proteins and a small peptide. In …

[HTML][HTML] Serology characteristics of SARS-CoV-2 infection after exposure and post-symptom onset

…, XJ Zhang, DH Wu, GL Zhou, WH Hou… - European …, 2020 - Eur Respiratory Soc
Background Timely diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection is a prerequisite for treatment and prevention. The serology characteristics …

[HTML][HTML] Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody

…, J Jiang, Z Li, S Li, H Zhao, L Yang, W Hou… - Nature …, 2017 - nature.com
Coxsackievirus A6 (CVA6) has recently emerged as a major cause of hand, foot and mouth
disease in children worldwide but no vaccine is available against CVA6 infections. Here, we …

HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation

…, X Guo, D Shi, J Li, L Jiang, S Sun, T Wang, W Hou… - Gut, 2019 - gut.bmj.com
Objective Developing a small animal model that accurately delineates the natural history of
hepatitis B virus (HBV) infection and immunopathophysiology is necessary to clarify the …

[HTML][HTML] Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization

…, X Yan, D Liu, Z Yin, Y Wu, Y Li, L Yang, W Hou… - Nature …, 2019 - nature.com
Enterovirus D68 (EV-D68) undergoes structural transformation between mature, cell-entry
intermediate (A-particle) and empty forms throughout its life cycle. Structural information for …

[HTML][HTML] Zika virus fatally infects wild type neonatal mice and replicates in central nervous system

S Li, N Armstrong, H Zhao, W Hou, J Liu, C Chen… - Viruses, 2018 - mdpi.com
Zika virus (ZIKV) has been defined as a teratogenic pathogen behind the increased number
of cases of microcephaly in French Polynesia, Brazil, Puerto Rico, and other South …

[HTML][HTML] Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation

H Ullah, W Hou, S Dakshanamurthy, Q Tang - Oncotarget, 2019 - ncbi.nlm.nih.gov
Due to the small number of molecular targets in viruses and the rapid evolution of viral
genes, it is very challenging to develop specific antiviral drugs. Viruses require host factors to …

Virus‐free and live‐cell visualizing SARS‐CoV‐2 cell entry for studies of neutralizing antibodies and compound inhibitors

Y Zhang, S Wang, Y Wu, W Hou, L Yuan… - Small …, 2021 - Wiley Online Library
The ongoing corona virus disease 2019 (COVID‐19) pandemic, caused by SARS‐CoV‐2
infection, has resulted in hundreds of thousands of deaths. Cellular entry of SARS‐CoV‐2, …