User profiles for Wanwei Zhang

Wanwei Zhang

Columbia University Irving Medical Center
Verified email at cumc.columbia.edu
Cited by 801

[HTML][HTML] Electrospun nanofibres containing antimicrobial plant extracts

W Zhang, S Ronca, E Mele - Nanomaterials, 2017 - mdpi.com
Over the last 10 years great research interest has been directed toward nanofibrous architectures
produced by electrospinning bioactive plant extracts. The resulting structures possess …

Big-data-based edge biomarkers: study on dynamical drug sensitivity and resistance in individuals

T Zeng, W Zhang, X Yu, X Liu, M Li… - Briefings in …, 2016 - academic.oup.com
Big-data-based edge biomarker is a new concept to characterize disease features based on
biomedical big data in a dynamical and network manner, which also provides alternative …

Specific regulation of BACH1 by the hotspot mutant p53R175H reveals a distinct gain-of-function mechanism

Z Su, N Kon, J Yi, H Zhao, W Zhang, Q Tang, H Li… - Nature cancer, 2023 - nature.com
Although the gain of function (GOF) of p53 mutants is well recognized, it remains unclear
whether different p53 mutants share the same cofactors to induce GOFs. In a proteomic screen, …

[HTML][HTML] Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression

…, Y Yang, AY Sarode, K Gollapalli, L Wu, W Zhang… - Nature …, 2023 - nature.com
Whole-genome sequencing of longitudinal tumor pairs representing transformation of
follicular lymphoma to high-grade B cell lymphoma with MYC and BCL2 rearrangements (double-…

Lineage specification of human dendritic cells is marked by IRF8 expression in hematopoietic stem cells and multipotent progenitors

J Lee, YJ Zhou, W Ma, W Zhang, A Aljoufi, T Luh… - Nature …, 2017 - nature.com
The origin and specification of human dendritic cells (DCs) have not been investigated at
the clonal level. Through the use of clonal assays, combined with statistical computation, to …

Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells

B Laffleur, J Lim, W Zhang, Y Chen, E Pefanis… - Nature …, 2021 - nature.com
Noncoding RNAs are exquisitely titrated by the cellular RNA surveillance machinery for
regulating diverse biological processes. The RNA exosome, the predominant 3′ RNA …

[PDF][PDF] 3D modeling of esophageal development using human PSC-derived basal progenitors reveals a critical role for notch signaling

Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang… - Cell stem cell, 2018 - cell.com
Pluripotent stem cells (PSCs) could provide a powerful system to model development of the
human esophagus, whose distinct tissue organization compared to rodent esophagus …

[PDF][PDF] Mechanism of noncoding RNA-associated N6-methyladenosine recognition by an RNA processing complex during IgH DNA recombination

L Nair, W Zhang, B Laffleur, MK Jha, J Lim, H Lee… - Molecular cell, 2021 - cell.com
Immunoglobulin heavy chain (IgH) locus-associated G-rich long noncoding RNA (SμGLT) is
important for physiological and pathological B cell DNA recombination. We demonstrate that …

RNA exosome drives early B cell development via noncoding RNA processing mechanisms

B Laffleur, CR Batista, W Zhang, J Lim, B Yang… - Science …, 2022 - science.org
B cell development is linked to successful V(D)J recombination, allowing B cell receptor
expression and ultimately antibody secretion for adaptive immunity. Germline noncoding RNAs (…

A new quaternion Kalman filter based foot-mounted IMU and UWB tightly-coupled method for indoor pedestrian navigation

…, K Yu, Y Li, S Zhang, W Zhang - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
In the field of indoor pedestrian navigation (IPN), the orientation information of a pedestrian
is often obtained by means of strap-down inertial navigation system (SINS). To deal with the …