User profiles for Wataru Nakai

Wataru NAKAI

Kyoto University
Verified email at kais.kyoto-u.ac.jp
Cited by 128

[PDF][PDF] An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

…, M Matsuda, C Ono, S Torii, K Kishida, H Jin, W Nakai… - Cell, 2021 - cell.com
Antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein
prevent SARS-CoV-2 infection. However, the effects of antibodies against other spike protein …

[HTML][HTML] A novel affinity-based method for the isolation of highly purified extracellular vesicles

W Nakai, T Yoshida, D Diez, Y Miyatake, T Nishibu… - Scientific reports, 2016 - nature.com
Extracellular vesicles (EVs) such as exosomes and microvesicles serve as messengers of
intercellular network, allowing exchange of cellular components between cells. EVs carry …

Comprehensive drowsiness level detection model combining multimodal information

M Sunagawa, S Shikii, W Nakai… - IEEE Sensors …, 2019 - ieeexplore.ieee.org
This paper presents a drowsiness detection model that is capable of sensing the entire range
of stages of drowsiness, from weak to strong. The key assumption underlying our approach …

SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses

M Kohyama, T Suzuki, W Nakai, C Ono… - International …, 2023 - academic.oup.com
Many patients with severe COVID-19 suffer from pneumonia and the elucidation of the
mechanisms underlying the development of this severe condition is important. The in vivo function …

Radial and vertical distributions of radiocesium in tree stems of Pinus densiflora and Quercus serrata 1.5 y after the Fukushima nuclear disaster

S Ohashi, N Okada, A Tanaka, W Nakai… - Journal of environmental …, 2014 - Elsevier
The radial and vertical distributions of radiocesium in tree stems were investigated to
understand radiocesium transfer to trees at an early stage of massive contamination from the …

[HTML][HTML] Characterization of the yeast Cdc7p/Dbf4p complex purified from insect cells: its protein kinase activity is regulated by Rad53p

M Kihara, W Nakai, S Asano, A Suzuki, K Kitada… - Journal of Biological …, 2000 - ASBMB
The yeast Saccharomyces cerevisiaeCdc7p/Dbf4p protein kinase complex was purified to
near homogeneity from insect cells. The complex efficiently phosphorylated yeast Mcm2p and …

The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines

…, K Akamatsu, C Ono, H Jin, K Kishida, W Nakai… - BioRxiv, 2021 - biorxiv.org
mRNA-based vaccines provide effective protection against most common SARS-CoV-2
variants. However, identifying likely breakthrough variants is critical for future vaccine …

Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules

H Jin, K Kishida, N Arase, S Matsuoka, W Nakai… - Science …, 2022 - science.org
Specific MHC class II alleles are strongly associated with susceptibility to various autoimmune
diseases. Although the primary function of MHC class II molecules is to present peptides …

The role of the Saccharomyces cerevisiae Cdc7–Dbf4 complex in the replication checkpoint

H Ogi, CZ Wang, W Nakai, Y Kawasaki, H Masumoto - Gene, 2008 - Elsevier
The Cdc7–Dbf4 complex is a conserved serine/threonine protein kinase essential for the
initiation of eukaryotic DNA replication. Although an mcm5–bob1 mutation bypasses lethality …

Sequence analysis of Stx2-converting phage VT2-Sa shows a great divergence in early regulation and replication regions

H Miyamoto, W Nakai, N Yajima, A Fujibayashi… - DNA …, 1999 - academic.oup.com
In enterohemorrhagic Escherichia coli, Shiga toxin is produced by lysogenic prophages. We
have isolated the prophage VT2-Sa that is responsible for production of Shiga toxin type 2 …