Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a respiratory disease
called coronavirus disease 2019 (COVID-19), the spread of which has led to a pandemic. …

Background The ongoing COVID-19 pandemic warrants accelerated efforts to test vaccine
candidates. We aimed to assess the safety and immunogenicity of an inactivated severe …

The SARS-CoV-2 B.1.1.529 (Omicron) variant contains 15 mutations of the receptor-binding
domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies requires …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.
2.12. 1, BA. 4 and BA. 5 exhibit higher transmissibility than the BA. 2 lineage 1. The receptor …

Since December 2019, a novel coronavirus SARS-CoV-2 has emerged and rapidly spread
throughout the world, resulting in a global public health emergency. The lack of vaccine and …

To discover new drugs to combat COVID-19, an understanding of the molecular basis of
SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of …

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. …

SARS-CoV-2 variants could induce immune escape by mutations on the receptor-binding
domain (RBD) and N-terminal domain (NTD). Here we report the humoral immune response to …

As the emerging variants of SARS-CoV-2 continue to drive the worldwide pandemic, there
is a constant demand for vaccines that offer more effective and broad-spectrum protection. …

There is an urgent need for vaccines against coronavirus disease 2019 (COVID-19) because
of the ongoing SARS-CoV-2 pandemic. Among all approaches, a messenger RNA (mRNA)…