User profiles for Wei Mi

Wei Mi

Assistant Professor, Yale University School of Medicine
Verified email at yale.edu
Cited by 968

Structural basis of MsbA-mediated lipopolysaccharide transport

W Mi, Y Li, SH Yoon, RK Ernst, T Walz, M Liao - Nature, 2017 - nature.com
Lipopolysaccharide (LPS) in the outer membrane of Gram-negative bacteria is critical for
the assembly of their cell envelopes. LPS synthesized in the cytoplasmic leaflet of the inner …

Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11. 2

…, Y Wang, LW Cai, C Jin, HY Zhang, J Yan, WF Mi… - Nature …, 2011 - nature.com
To identify susceptibility loci for schizophrenia, we performed a two-stage genome-wide
association study (GWAS) of schizophrenia in the Han Chinese population (GWAS: 746 …

[HTML][HTML] Proteome analysis of hepatocellular carcinoma by two-dimensional difference gel electrophoresis: novel protein markers in hepatocellular carcinoma tissues

…, X Du, M Lu, C Hao, Z Lu, W Mi, S Wu, H Wei… - Molecular & cellular …, 2007 - ASBMB
Hepatocellular carcinoma (HCC) is a highly malignant tumor, and chronic infection with
hepatitis B virus is one of its major risk factors. To identify the proteins involved in HCC …

Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3

S Schoebel, W Mi, A Stein, S Ovchinnikov, R Pavlovicz… - Nature, 2017 - nature.com
Misfolded endoplasmic reticulum proteins are retro-translocated through the membrane into
the cytosol, where they are poly-ubiquitinated, extracted from the membrane, and degraded …

Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex

X Wu, M Siggel, S Ovchinnikov, W Mi, V Svetlov… - Science, 2020 - science.org
INTRODUCTION Protein homeostasis in the endoplasmic reticulum (ER) is maintained by a
quality control system. When a newly synthesized ER protein misfolds, it is ultimately …

IPAC image processing and data archiving for the Palomar Transient Factory

…, E Jackson, E Hacopeans, W Mi… - Publications of the …, 2014 - iopscience.iop.org
The Palomar Transient Factory (PTF) is a multiepochal robotic survey of the northern sky
that acquires data for the scientific study of transient and variable astrophysical phenomena. …

[HTML][HTML] Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice

XY Zhang, JB Cao, LM Zhang, YF Li, WD Mi - Journal of …, 2015 - Springer
Background Neuroinflammation often results in enduring cognitive impairment and is a risk
factor for postoperative cognitive dysfunction. There are currently no effective treatments for …

[HTML][HTML] Haemodynamic and electroencephalograph responses to intubation during induction with propofol or propofol/fentanyl

WD Mi, T Sakai, S Takahashi, A Matsuki - Canadian journal of anaesthesia, 1998 - Springer
Purpose To observe the changes in EEG bispectral index (BIS), 95% spectral edge frequency
(95% SEF) and median frequency (MF) with haemodynamic changes to intubation during …

[HTML][HTML] Acetaminophen attenuates lipopolysaccharide-induced cognitive impairment through antioxidant activity

…, XY Zhang, J Yu, YY Zhang, YZ Zhang, WD Mi - Journal of …, 2017 - Springer
Background Considerable evidence has shown that neuroinflammation and oxidative stress
play an important role in the pathophysiology of postoperative cognitive dysfunction (POCD) …

Experimental study on the improvement of marine clay slurry by electroosmosis-vacuum preloading

J Wang, J Ma, F Liu, W Mi, Y Cai, H Fu… - Geotextiles and …, 2016 - Elsevier
Laboratory tests were conducted on marine clay slurry to investigate the feasibility and
effectiveness of a combined electroosmosis-vacuum preloading method in tideland reclamation. …