Acute myeloid leukemia (AML) is driven and sustained by leukemia stem cells (LSCs) with
unlimited self-renewal capacity and resistance to chemotherapy. Mutation in the TP53 tumor …

Acute myeloid leukemia (AML) harboring inv(16)(p13q22) expresses high levels of miR-126.
Here we show that the CBFB-MYH11 (CM) fusion gene upregulates miR-126 expression …

Myelodysplastic syndrome (MDS), a largely incurable hematological malignancy, is derived
from aberrant clonal hematopoietic stem/progenitor cells (HSPCs) that persist after …

The maintenance and functional integrity of long-term hematopoietic stem cells (LT-HSCs)
is critical for lifelong hematopoietic regeneration. Histone deacetylases (HDACs) modulate …

Proteins accumulated in dry, stratified Arabidopsis seeds or young seedlings, totaled 1100 to
1300 depending on the time of sampling, were analyzed by using immobilized pH gradient …

The global effect of ubiquitin–proteasome (UP) inhibitors on leukemic cell proteome was
analysed. A total of 39 protein spots, affected by UP inhibitors, were identified, including 11 new …

Psoriasis-specific proteins dysregulated in keratinocytes and involved in the pathophysiological
process of psoriasis remains elusive. We report here that epidermal galectin-3 …

Objective The specific autoantibodies and antigens that mediate systemic lupus erythematosus
(SLE)–related organ injuries remain largely unknown. This study was undertaken to …

These findings apply the theory of state transitions to model the initiation and development of
acute myeloid leukemia, identifying transcriptomic perturbations that accurately predict time …

Outbreaks in humans, caused by Streptococcus suis serotype 2 (SS2), were reported in 1998
and 2005 in China. However, the mechanism of SS2‐associated infection remains unclear…