User profiles for Wenduo Ye
Wenduo YeUTSW Verified email at UTsouthwestern.edu Cited by 946 |
Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation
The molecular mechanisms underlying atrial fibrillation, the most common sustained cardiac
arrhythmia, remain poorly understood. Genome-wide association studies uncovered a …
arrhythmia, remain poorly understood. Genome-wide association studies uncovered a …
A common Shox2–Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node
In humans, atrial fibrillation is often triggered by ectopic pacemaking activity in the myocardium
sleeves of the pulmonary vein (PV) and systemic venous return. The genetic programs …
sleeves of the pulmonary vein (PV) and systemic venous return. The genetic programs …
Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling
… We dedicate this work to the memory of Wenduo Ye, an exceptional colleague and caring
friend who generated data for this study. We thank Jose Cabrera for graphics, John McAnally …
friend who generated data for this study. We thank Jose Cabrera for graphics, John McAnally …
ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression
Direct reprogramming of fibroblasts to cardiomyocytes represents a potential means of
restoring cardiac function following myocardial injury. AKT1 in the presence of four cardiogenic …
restoring cardiac function following myocardial injury. AKT1 in the presence of four cardiogenic …
[PDF][PDF] Cardiac reprogramming factors synergistically activate genome-wide cardiogenic stage-specific enhancers
The cardiogenic transcription factors (TFs) Mef2c, Gata4, and Tbx5 can directly reprogram
fibroblasts to induced cardiac-like myocytes (iCLMs), presenting a potential source of cells for …
fibroblasts to induced cardiac-like myocytes (iCLMs), presenting a potential source of cells for …
[HTML][HTML] Genetic regulation of sinoatrial node development and pacemaker program in the venous pole
The definitive sinoatrial node (SAN), the primary pacemaker of the mammalian heart, develops
from part of pro-pacemaking embryonic venous pole that expresses both Hcn4 and the …
from part of pro-pacemaking embryonic venous pole that expresses both Hcn4 and the …
[HTML][HTML] BMPRIA mediated signaling is essential for temporomandibular joint development in mice
The central importance of BMP signaling in the development and homeostasis of synovial
joint of appendicular skeleton has been well documented, but its role in the development of …
joint of appendicular skeleton has been well documented, but its role in the development of …
FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling
Odontoblasts and osteoblasts develop from multipotent craniofacial neural crest cells during
tooth and jawbone development, but the mechanisms that specify and sustain their …
tooth and jawbone development, but the mechanisms that specify and sustain their …
[HTML][HTML] The short stature homeobox 2 (Shox2)-bone morphogenetic protein (BMP) pathway regulates dorsal mesenchymal protrusion development and its temporary …
The atrioventricular (AV) junction plays a critical role in chamber septation and transmission
of cardiac conduction pulses. It consists of structures that develop from embryonic dorsal …
of cardiac conduction pulses. It consists of structures that develop from embryonic dorsal …
[HTML][HTML] Karyopherins in nuclear transport of homeodomain proteins during development
Homeodomain proteins are crucial transcription factors for cell differentiation, cell proliferation
and organ development. Interestingly, their homeodomain signature structure is important …
and organ development. Interestingly, their homeodomain signature structure is important …