User profiles for Wenjia Chen
Chen WenjiaNational University of Singapore Verified email at nus.edu.sg Cited by 2616 |
Risk of cardiovascular comorbidity in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
Background Chronic obstructive pulmonary disease (COPD) is a systemic inflammatory
disorder associated with increased comorbid prevalence of cardiovascular diseases. We aimed …
disorder associated with increased comorbid prevalence of cardiovascular diseases. We aimed …
Overall and cause‐specific mortality in patients with systemic lupus erythematosus: a meta‐analysis of observational studies
M Yurkovich, K Vostretsova, W Chen… - Arthritis care & …, 2014 - Wiley Online Library
Objective To determine the magnitude of risk from all‐cause and cause‐specific mortality in
patients with systemic lupus erythematosus (SLE) compared to the general population …
patients with systemic lupus erythematosus (SLE) compared to the general population …
Tripterygium wilfordii: An inspiring resource for rheumatoid arthritis treatment
Y Zhang, X Mao, W Li, W Chen, X Wang… - Medicinal research …, 2021 - Wiley Online Library
Tripterygium wilfordii Hook F (TwHF)‐based therapy is among the most efficient and crucial
therapeutics for the treatment of rheumatoid arthritis (RA), which indicates that TwHF is a …
therapeutics for the treatment of rheumatoid arthritis (RA), which indicates that TwHF is a …
Mortality in ANCA-associated vasculitis: ameta-analysis of observational studies
Objective To determine the magnitude of all-cause mortality risk in patients with antineutrophil
cytoplasmic antibodies-associated vasculitis (AAV) compared with the general population …
cytoplasmic antibodies-associated vasculitis (AAV) compared with the general population …
The preventable burden of productivity loss due to suboptimal asthma control: a population-based study
Background Productivity loss is an overlooked aspect of the burden of chronic health conditions.
While modern guidelines emphasize achieving clinical control in asthma management, …
While modern guidelines emphasize achieving clinical control in asthma management, …
[HTML][HTML] Treatment outcomes from community-based drug resistant tuberculosis treatment programs: a systematic review and meta-analysis
Background There is increasing evidence that community-based treatment of drug resistant
tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based …
tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based …
Excess economic burden of comorbidities in COPD: a 15-year population-based study
A better understanding of the true burden of chronic obstructive pulmonary disease (COPD)
needs to consider the implications of comorbidities. This study comprehensively examined …
needs to consider the implications of comorbidities. This study comprehensively examined …
[HTML][HTML] Preclinical investigation of artesunate as a therapeutic agent for hepatocellular carcinoma via impairment of glucosylceramidase-mediated autophagic …
W Chen, Z Ma, L Yu, X Mao, N Ma, X Guo… - … & Molecular Medicine, 2022 - nature.com
Artesunate (ART) has been indicated as a candidate drug for hepatocellular carcinoma (HCC).
Glucosylceramidase (GBA) is required for autophagic degradation. Whether ART …
Glucosylceramidase (GBA) is required for autophagic degradation. Whether ART …
[HTML][HTML] Impact of initiating biologics in patients with severe asthma on long-term oral corticosteroids or frequent rescue steroids (GLITTER): data from the International …
W Chen, TN Tran, M Sadatsafavi, R Murray… - The Journal of Allergy …, 2023 - Elsevier
BACKGROUND Effectiveness of biologics has neither been established in patients with high
oral corticosteroid exposure (HOCS), nor been compared to effectiveness of continuing with …
oral corticosteroid exposure (HOCS), nor been compared to effectiveness of continuing with …
[HTML][HTML] Cost-effectiveness of bronchial thermoplasty, omalizumab, and standard therapy for moderate-to-severe allergic asthma
Background Bronchial thermoplasty (BT) is a recently developed treatment for patients with
moderate-to-severe asthma. A few studies have suggested the clinical efficacy of this …
moderate-to-severe asthma. A few studies have suggested the clinical efficacy of this …