Rationale: KRAS is one of the most frequently mutated oncogenes in cancers. The protein's
picomolar affinity for GTP/GDP and smooth protein structure resulting in the absence of …

Computation offloading is considered as a promising method to improve computation
performance of Intelligent Vehicles (IVs), where IVs can offload resource-hungry applications to …

RNA editing is a post-transcriptional modification with a cell-specific manner and important
biological implications. Although single-cell RNA-seq (scRNA-seq) is an effective method for …

Herein, we report the development of efficient inhibitors of reverse transcriptase (RT) of HIV-1
based on indole-alkyl trifluoropyruvate derivatives by a TZM-bl cell assay. The inhibitory …

In this study, a series of novel gossypol derivatives were synthesized and screened in vitro
for their anti-HIV-1 and anti-H 5 N 1 activities, respectively. Replacing the aldehyde groups of …

T20 and maraviroc are the only two currently available entry inhibitors that have shown efficacy
in treating HIV-1-infected individuals who have failed to respond to first-line antiretroviral …

Quantum wires, as a smallest electronic conductor, are expected to be a fundamental component
in all quantum architectures. The electronic conductance in quantum wires, however, is …

Human mesenchymal stem cells (hMSCs) are widely used in clinical research because of
their multipotential, immunomodulatory, and reparative properties. Previous studies …

High-definition (HD) maps can provide an accurate representation of the road ahead and
information on the surrounding environment, which is the key to the success of autonomous …

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by persistent
deficits in social communication and stereotyped behaviors. Although major advances in …