Potential antiviral activity of isorhamnetin against SARS‐CoV‐2 spike pseudotyped virus in vitro

Y Zhan, W Ta, W Tang, R Hua, J Wang… - Drug Development …, 2021 - Wiley Online Library
Coronavirus Disease 2019 (COVID‐19) cases and deaths are still rising worldwide, there is
currently no effective treatment for severe inflammation and acute lung injury caused by new …

Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus

…, S Wang, P Liang, T Hu, J Lu, X Wang, H Zhou, W Ta… - Phytomedicine, 2020 - Elsevier
Background The novel coronavirus disease (2019-nCoV) has been affecting global health
since the end of 2019 and there is no sign that the epidemic is abating . The major issue for …

[HTML][HTML] A review on increasing the targeting of PAMAM as carriers in glioma therapy

X Li, W Ta, R Hua, J Song, W Lu - Biomedicines, 2022 - mdpi.com
Glioma is an invasive brain cancer, and it is difficult to achieve desired therapeutic effects
due to the high postoperative recurrence rate and limited efficacy of drug therapy hindered by …

Customizable dual-fluorescent nanoparticles for tracing and quantifying of cell transport

W Ta, X Li, J Song, R Hua, Y Zheng… - International Journal of …, 2023 - Taylor & Francis
Purpose Nanotechnology-based drug delivery systems (nano-DDS) have been developed
to be a promising strategy to improve the efficacy, safety, physicochemical and …

In vitro blood-brain barrier models from different species: an overview on permeability associated with drug delivery.

W Ta, R Hua, X Li, J Song, W Lu - Journal of Chinese …, 2023 - search.ebscohost.com
The specific structure of the blood-brain barrier (BBB) leads to the low permeability of central
nervous system (CNS) drugs. Many cell-based in vitro BBB models have been developed …

Elucidation the mechanism of the active ingredient imperatorin promoting drug absorption in cell model

W Ta, J Wang, J Song, X Li, J Wang… - Journal of Pharmacy …, 2024 - academic.oup.com
Imperatorin (IMP) is the main bioactive furanocoumarin of Angelicae dahuricae radix, which
is a well-known traditional Chinese medicine. The purpose of this study was to elucidate the …

Development a multicellular model to investigate the intestinal-vascular transport barrier of drug

J Wang, C Han, W Ta, R Liu, X He, W Lu - Journal of Drug Delivery Science …, 2021 - Elsevier
Multicellular transport models for drug have received more attention and research due to a
closer physiological structure. A Caco-2/EA.hy926 cell co-culture model was constructed to …

[HTML][HTML] Comparison of intestinal absorption characteristics between rhubarb traditional Chinese medicine preparation and activity ingredients using in situ and in vitro …

W Ta, X Yang, J Wang, C Han, R Hua, W Lu - Chinese Herbal Medicines, 2023 - Elsevier
Objective The intestinal absorption characteristics of active ingredients are very important
for oral administration of traditional Chinese medicine (TCM) to achieve the desired …

[HTML][HTML] Effects of Al on precipitation behavior of Ti-Nb-Ta-Zr refractory high entropy alloys

J Wen, X Chu, Y Cao, N Li - Metals, 2021 - mdpi.com
… of the Ti-Nb-Ta-Zr RHEAs with the addition of Al still remains unclear, which has become
an urgent issue. In this work, we fabricated a series of Al-contained Ti-Nb-Ta-Zr RHEAs and …

Study on the Promoting Effect and Mechanism of Imperatorin on the Absorption of Drugs in Cell Model

W Ta, J Wang, J Song, X Li, R Hua, W Lu - Available at SSRN 4222926 - papers.ssrn.com
Wenjing Ta performed the experiment and wrote the manuscript. Jie Wang performed the
experiment and provided experimental guidance. Jihong Song, Xinyue Li, and Ruochen Hua …