Inferring the timing and strength of natural selection and gene migration in the evolution of chicken from ancient DNA data

W Lyu, X Dai, M Beaumont, F Yu… - Molecular Ecology …, 2022 - Wiley Online Library
With the rapid growth of the number of sequenced ancient genomes, there has been
increasing interest in using this new information to study past and present adaptation. Such an …

Estimating temporally variable selection intensity from ancient DNA data

Z He, X Dai, W Lyu, M Beaumont… - Molecular Biology and …, 2023 - academic.oup.com
Novel technologies for recovering DNA information from archaeological and historical
specimens have made available an ever-increasing amount of temporally spaced genetic …

The role of depth and flatness of a potential energy surface in chemical reaction dynamics

W Lyu, S Naik, S Wiggins - Regular and Chaotic Dynamics, 2020 - Springer
In this study, we analyze how changes in the geometry of a potential energy surface in terms
of depth and flatness can affect the reaction dynamics. We formulate depth and flatness in …

Hamiltonian pitchfork bifurcation in transition across index-1 saddles

W Lyu, S Naik, S Wiggins - … in Nonlinear Science and Numerical Simulation, 2021 - Elsevier
We study the effect of changes in the parameters of a two dimensional potential energy surface
on the phase space structures relevant for chemical reaction dynamics. The changes in …

Moment-based approximations for the Wright-Fisher model of population dynamics under natural selection at two linked loci

Z He, W Lyu, M Beaumont, F Yu - bioRxiv, 2021 - biorxiv.org
Properly modelling genetic recombination and local linkage has been shown to bring a
significant improvement to the inference of natural selection from time series genetic data under …

Estimating temporally variable selection intensity from ancient DNA data with the flexibility of modelling linkage and epistasis

Z He, X Dai, W Lyu, M Beaumont… - Molecular Ecology …, 2023 - Wiley Online Library
Innovations in ancient DNA (aDNA) preparation and sequencing technologies have
exponentially increased the quality and quantity of aDNA data extracted from ancient biological …

[PDF][PDF] UPOsHam: A Python package for computing unstable periodic orbits in two-degree-of-freedom Hamiltonian systems

W Lyu, S Naik, S Wiggins - Journal of Open …, 2020 - research-information.bris.ac.uk
The Python package, UPOsHam, is a collection of three methods in the form of submodules
under uposham for computing UPOs around index-1 saddles in the bottleneck of …

Beyond Gaussian Quantum Channels: A model case

D Speed, W Lyu, R Schubert - arXiv preprint arXiv:2305.08467, 2023 - arxiv.org
Gaussian quantum channels are well understood and have many applications, eg, in Quantum
Information Theory and in Quantum Optics. For more general quantum channels one can …

Elementary exposition of realizing phase space structures relevant to chemical reaction dynamics

W Lyu, S Naik, S Wiggins - arXiv preprint arXiv:2004.05709, 2020 - arxiv.org
In this article, we review the analytical and numerical approaches for computing the phase
space structures in two degrees-of-freedom Hamiltonian systems that arise in chemical …

Estimating temporally variable selection intensity from ancient DNA data II

W Lyu, X Dai, M Beaumont, F Yu, Z He - bioRxiv, 2023 - biorxiv.org
Recent technological innovations, such as next generation sequencing and DNA hybridisation
enrichment, have made it possible to recover DNA information from historical and …