User profiles for Wenying Shou
 | Wenying ShouProfessor, University College London, Department of Genetics, Evolution and Environment Verified email at ucl.ac.uk Cited by 5385 |
Synthetic cooperation in engineered yeast populations
Cooperative interactions are key to diverse biological phenomena ranging from multicellularity
to mutualism. Such diversity makes the ability to create and control cooperation desirable …
to mutualism. Such diversity makes the ability to create and control cooperation desirable …
Challenges in microbial ecology: building predictive understanding of community function and dynamics
The importance of microbial communities (MCs) cannot be overstated. MCs underpin the
biogeochemical cycles of the earth’s soil, oceans and the atmosphere, and perform ecosystem …
biogeochemical cycles of the earth’s soil, oceans and the atmosphere, and perform ecosystem …
Engineering microbial consortia for controllable outputs
Much research has been invested into engineering microorganisms to perform desired
biotransformations; nonetheless, these efforts frequently fall short of expected results due to the …
biotransformations; nonetheless, these efforts frequently fall short of expected results due to the …
Using artificial systems to explore the ecology and evolution of symbioses
The web of life is weaved from diverse symbiotic interactions between species. Symbioses
vary from antagonistic interactions such as competition and predation to beneficial …
vary from antagonistic interactions such as competition and predation to beneficial …
[HTML][HTML] Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
Exit from mitosis in budding yeast requires a group of essential proteins—including the GTPase
Tem1 and the protein phosphatase Cdc14—that downregulate cyclin-dependent kinase …
Tem1 and the protein phosphatase Cdc14—that downregulate cyclin-dependent kinase …
[HTML][HTML] Data-driven causal analysis of observational biological time series
AE Yuan, W Shou - Elife, 2022 - elifesciences.org
Complex systems are challenging to understand, especially when they defy manipulative
experiments for practical or ethical reasons. Several fields have developed parallel …
experiments for practical or ethical reasons. Several fields have developed parallel …
[HTML][HTML] Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
The Sir2 protein mediates gene silencing and repression of recombination at the rDNA repeats
in budding yeast. Here we show that Sir2 executes these functions as a component of a …
in budding yeast. Here we show that Sir2 executes these functions as a component of a …
Lotka-Volterra pairwise modeling fails to capture diverse pairwise microbial interactions
10.7554/eLife.25051.001 Pairwise models are commonly used to describe many-species
communities. In these models, an individual receives additive fitness effects from pairwise …
communities. In these models, an individual receives additive fitness effects from pairwise …
Phosphorylation by cyclin B-Cdk underlies release of mitotic exit activator Cdc14 from the nucleolus
R Azzam, SL Chen, W Shou, AS Mah, G Alexandru… - Science, 2004 - science.org
Budding yeast protein phosphatase Cdc14 is sequestered in the nucleolus in an inactive state
during interphase by the anchor protein Net1. Upon entry into anaphase, the Cdc14 early …
during interphase by the anchor protein Net1. Upon entry into anaphase, the Cdc14 early …
Strong inter-population cooperation leads to partner intermixing in microbial communities
10.7554/eLife.00230.001 Patterns of spatial positioning of individuals within microbial
communities are often critical to community function. However, understanding patterning in natural …
communities are often critical to community function. However, understanding patterning in natural …