Study of the interactions established between the viral glycoproteins and their host receptors
is of critical importance for a better understanding of virus entry into cells. The novel …

Inducing macromolecular interactions with small molecules to activate cellular signaling is a
challenging goal. PROTACs (proteolysis-targeting chimeras) are bifunctional molecules that …

Active biodegradable packaging are being developed from biodegradable biopolymers
which may solve the environmental problems caused by petroleum-based materials (plastics), …

E3 ubiquitin ligases are key enzymes within the ubiquitin proteasome system which catalyze
the ubiquitination of proteins, targeting them for proteasomal degradation. E3 ligases are …

Protein S-glutathionylation is a reversible post-translational modification regulating sulfhydryl
homeostasis. However, little is known about the proteins and pathways regulated by S-…

The recent emergence of highly transmissible SARS-CoV-2 variants illustrates the urgent
need to better understand the molecular details of the virus binding to its host cell and to …

Biodegradable films constructed from food ingredients are being developed for food coating
and packaging applications to create more sustainable and environmentally friendly …

In this study, novel copillar[4+1]arenes were used as central heteromultivalent scaffolds via
orthogonal couplings with a series of biologically relevant molecules such as carbohydrates, …

Chemical cross-linking mass spectrometry (XL-MS) is a powerful technology for obtaining
protein structural information and studying protein–protein interactions. We report phospho-…

A number of vinylsulfonamides were synthesized and screened to identify reagents that can
be used to modify octreotide under biological pH and room temperature with improved …