User profiles for Wesley K. Thompson

Wesley Thompson

The Laureate Institute for Brain Research
Verified email at laureateinstitute.org
Cited by 32895

[HTML][HTML] Reproducible brain-wide association studies require thousands of individuals

…, DJ Greene, SE Petersen, H Garavan, WK Thompson… - Nature, 2022 - nature.com
Magnetic resonance imaging (MRI) has transformed our understanding of the human brain
through well-replicated mapping of abilities to specific structures (for example, lesion studies) …

Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

…, M Soules, J Diaz, OR de Leon, WK Thompson… - Neuroimage, 2019 - Elsevier
The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing, nationwide
study of the effects of environmental influences on behavioral and brain development in …

Association between older age and more successful aging: critical role of resilience and depression

DV Jeste, GN Savla, WK Thompson… - American Journal of …, 2013 - Am Psychiatric Assoc
Objective There is growing public health interest in understanding and promoting successful
aging. While there has been some exciting empirical work on objective measures of …

[PDF][PDF] Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

OA Andreassen, S Djurovic, WK Thompson… - The American Journal of …, 2013 - cell.com
Several lines of evidence suggest that genome-wide association studies (GWASs) have the
potential to explain more of the "missing heritability" of common complex phenotypes. …

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

…, S Onengut-Gumuscu, SS Rich, WK Thompson… - Nature …, 2013 - nature.com
Primary sclerosing cholangitis (PSC) is a severe liver disease of unknown etiology leading to
fibrotic destruction of the bile ducts and ultimately to the need for liver transplantation 1 , 2 , …

[HTML][HTML] Genetic assessment of age-associated Alzheimer disease risk: development and validation of a polygenic hazard score

…, HJ Cabral, LA Cupples, WK Thompson… - PLoS …, 2017 - journals.plos.org
Background Identifying individuals at risk for developing Alzheimer disease (AD) is of utmost
importance. Although genetic studies have identified AD-associated SNPs in APOE and …

[HTML][HTML] Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

OA Andreassen, WK Thompson, AJ Schork… - PLoS …, 2013 - journals.plos.org
Several lines of evidence suggest that genome-wide association studies (GWAS) have the
potential to explain more of the “missing heritability” of common complex phenotypes. …

[HTML][HTML] All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

AJ Schork, WK Thompson, P Pham, A Torkamani… - PLoS …, 2013 - journals.plos.org
Recent results indicate that genome-wide association studies (GWAS) have the potential to
explain much of the heritability of common complex phenotypes, but methods are lacking to …

The pediatric imaging, neurocognition, and genetics (PING) data repository

…, N Akshoomoff, H Bartsch, E Newman, WK Thompson… - Neuroimage, 2016 - Elsevier
The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING)
study was to create a large repository of standardized measurements of behavioral and …

Development and aging of cortical thickness correspond to genetic organization patterns

…, H Bartsch, CH Chen, WK Thompson… - Proceedings of the …, 2015 - National Acad Sciences
There is a growing realization that early life influences have lasting impact on brain function
and structure. Recent research has demonstrated that genetic relationships in adults can be …