Pattern recognition molecules activated by Chlamydia muridarum infection of cloned murine oviduct epithelial cell lines

WA Derbigny, MS Kerr, RM Johnson - The Journal of Immunology, 2005 - journals.aai.org
Chlamydia trachomatis is the most common bacterial sexually transmitted disease in the
United States and a major cause of female infertility due to infection-induced Fallopian tube …

Identifying a role for Toll-like receptor 3 in the innate immune response to Chlamydia muridarum infection in murine oviduct epithelial cells

WA Derbigny, LTR Shobe, JC Kamran… - Infection and …, 2012 - Am Soc Microbiol
Because epithelial cells are the major cell type productively infected with Chlamydia during
genital tract infections, the overall goal of our research was to understand the contribution of …

The Chlamydia muridarum-induced IFN-β response is TLR3-dependent in murine oviduct epithelial cells

WA Derbigny, RM Johnson, KS Toomey… - The Journal of …, 2010 - journals.aai.org
Epithelial cells lining the murine genital tract act as sentinels for microbial infection, play a
major role in the initiation of the early inflammatory response, and can secrete factors that …

Chlamydia muridarum Infection Elicits a Beta Interferon Response in Murine Oviduct Epithelial Cells Dependent on Interferon Regulatory Factor 3 and TRIF

WA Derbigny, SC Hong, MS Kerr, M Temkit… - Infection and …, 2007 - Am Soc Microbiol
Chlamydia trachomatis is the most common sexually transmitted bacterial infection in the
United States. Utilizing cloned murine oviduct epithelial cell lines, we previously identified Toll-…

[HTML][HTML] Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice

…, R Kumar, GE Sandusky, XF Yang, WA Derbigny - PLoS …, 2018 - journals.plos.org
Chlamydia trachomatis urogenital serovars primarily replicate in epithelial cells lining the
reproductive tract. Epithelial cells recognize Chlamydia through cell surface and cytosolic …

Cellulose acetate electrophoresis of hemoglobin

R Kumar, WA Derbigny - … Separation of Proteins: Methods and Protocols, 2019 - Springer
The electrophoresis on cellulose acetate membrane is most widely used because of its
simplicity, and is without the use of any sophisticated instrument other than electrophoresis …

[HTML][HTML] TLR3 deficiency exacerbates the loss of epithelial barrier function during genital tract Chlamydia muridarum infection

…, L Liu, N Ramos-Solis, CI Seye, WA Derbigny - PLoS …, 2019 - journals.plos.org
Problem Chlamydia trachomatis infections are often associated with acute syndromes including
cervicitis, urethritis, and endometritis, which can lead to chronic sequelae such as pelvic …

Interaction of the equine herpesvirus 1 EICP0 protein with the immediate-early (IE) protein, TFIIB, and TBP may mediate the antagonism between the IE and EICP0 …

SK Kim, HK Jang, RA Albrecht, WA Derbigny… - Journal of …, 2003 - Am Soc Microbiol
The equine herpesvirus 1 (EHV-1) immediate-early (IE) and EICP0 proteins are potent trans-activators
of EHV-1 promoters; however, in transient-transfection assays, the IE protein …

EHV-1 EICP22 protein sequences that mediate its physical interaction with the immediate-early protein are not sufficient to enhance the trans-activation activity of the …

WA Derbigny, SK Kim, HK Jang, DJ O'Callaghan - Virus research, 2002 - Elsevier
The early 293 amino acid EICP22 protein (EICP22P) of equine herpesvirus 1 localizes
within the nucleus and functions as an accessory regulatory protein (J. Virol. 68 (1994) 4329). …

Toll-like receptor 3 deficiency leads to altered immune responses to Chlamydia trachomatis infection in human oviduct epithelial cells

…, L Liu, N Ramos-Solis, Y Li, WA Derbigny - Infection and …, 2019 - Am Soc Microbiol
Reproductive tract pathology caused by Chlamydia trachomatis infection is an important
global cause of human infertility. To better understand the mechanisms associated with …