User profiles for Will van Treuren

Will Van Treuren

PhD Microbiology and Immunology, Interface Biosciences
Verified email at interface.bio
Cited by 23473

The intestinal metabolome: an intersection between microbiota and host

LK Ursell, HJ Haiser, W Van Treuren, N Garg… - Gastroenterology, 2014 - Elsevier
Recent advances that allow us to collect more data on DNA sequences and metabolites
have increased our understanding of connections between the intestinal microbiota and …

[PDF][PDF] The treatment-naive microbiome in new-onset Crohn's disease

…, LA Denson, Y Vázquez-Baeza, W Van Treuren… - Cell host & …, 2014 - cell.com
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked
to host pathways that implicate an underlying role for aberrant immune responses to …

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

…, VR Subramaniam, A Swarup, M Swift, W Van Treuren… - Science, 2022 - science.org
Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …

Analysis of composition of microbiomes: a novel method for studying microbial composition

S Mandal, W Van Treuren, RA White… - Microbial ecology in …, 2015 - Taylor & Francis
Background Understanding the factors regulating our microbiota is important but requires
appropriate statistical methodology. When comparing two or more populations most existing …

Longitudinal analysis of microbial interaction between humans and the indoor environment

…, LK Ursell, Y Vázquez-Baeza, W Van Treuren… - Science, 2014 - science.org
The bacteria that colonize humans and our built environments have the potential to influence
our health. Microbial communities associated with seven families and their homes over 6 …

Correlation detection strategies in microbial data sets vary widely in sensitivity and precision

S Weiss, W Van Treuren, C Lozupone, K Faust… - The ISME …, 2016 - academic.oup.com
Will Van Treuren … Sophie Weiss and Will Van Treuren: These authors contributed equally to
this work… , or those that benefit each other, will positively correlate across samples. In contrast…

A metabolomics pipeline for the mechanistic interrogation of the gut microbiome

S Han, W Van Treuren, CR Fischer, BD Merrill… - Nature, 2021 - nature.com
Gut microorganisms modulate host phenotypes and are associated with numerous health
effects in humans, ranging from host responses to cancer immunotherapy to metabolic …

[HTML][HTML] Subsistence strategies in traditional societies distinguish gut microbiomes

…, LK Ursell, Z Zech Xu, W Van Treuren… - Nature …, 2015 - nature.com
Recent studies suggest that gut microbiomes of urban-industrialized societies are different
from those of traditional peoples. Here we examine the relationship between lifeways and gut …

[PDF][PDF] Longitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

…, T Zheng, N Bar, G Frost, AJ Johnson, W van Treuren… - Cell, 2020 - cell.com
The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI)
disorders. Determining its mechanistic role in disease has been difficult due to apparent …

Microbial community assembly and metabolic function during mammalian corpse decomposition

JL Metcalf, ZZ Xu, S Weiss, S Lax, W Van Treuren… - Science, 2016 - science.org
Vertebrate corpse decomposition provides an important stage in nutrient cycling in most
terrestrial habitats, yet microbially mediated processes are poorly understood. Here we combine …