Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …

The genetic basis of autism spectrum disorder (ASD) is known to consist of contributions from
de novo mutations in variant-intolerant genes. We hypothesize that rare inherited structural …

Handedness and brain asymmetry have been linked to neurodevelopmental disorders such
as dyslexia and schizophrenia. The genetic nature of this correlation is not understood. …

Humans display structural and functional asymmetries in brain organization, strikingly with
respect to language and handedness. The molecular basis of these asymmetries is unknown. …

Approximately 90% of humans are right-handed. Handedness is a heritable trait, yet the
genetic basis is not well understood. Here we report a genome-wide association study for a …

Reading and language abilities are heritable traits that are likely to share some genetic
influences with each other. To identify pleiotropic genetic variants affecting these traits, we first …

Genetic studies of autism spectrum disorder (ASD) have established that de novo duplications
and deletions contribute to risk. However, ascertainment of structural variants (SVs) has …

Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high
impact on school and psychosocial development and high comorbidity with conditions like …

De novo mutations arising on the paternal chromosome make the largest known contribution
to autism risk, and correlate with paternal age at the time of conception. The recurrence risk …

While germline copy-number variants (CNVs) contribute to schizophrenia (SCZ) risk, the
contribution of somatic CNVs (sCNVs)—present in some but not all cells—remains unknown. …