User profiles for William J. Wulftange
 | William J. WulftangeCase Western Reserve University Verified email at case.edu Cited by 533 |
A nanoporous two-dimensional polymer by single-crystal-to-single-crystal photopolymerization
In contrast to the wide number and variety of available synthetic routes to conventional
linear polymers, the synthesis of two-dimensional polymers and unambiguous proof of their …
linear polymers, the synthesis of two-dimensional polymers and unambiguous proof of their …
Real-time imaging of nanobubble ultrasound contrast agent flow, extravasation, and diffusion through an extracellular matrix using a microfluidic model
Lipid shell-stabilized nanoparticles with a perfluorocarbon gas-core, or nanobubbles, have
recently attracted attention as a new contrast agent for molecular ultrasound imaging and …
recently attracted attention as a new contrast agent for molecular ultrasound imaging and …
Sickle red blood cell‐derived extracellular vesicles activate endothelial cells and enhance sickle red cell adhesion mediated by von Willebrand factor
Endothelial activation and sickle red blood cell (RBC) adhesion are central to the pathogenesis
of sickle cell disease (SCD). Quantitatively, RBC‐derived extracellular vesicles (REVs) …
of sickle cell disease (SCD). Quantitatively, RBC‐derived extracellular vesicles (REVs) …
[HTML][HTML] OcclusionChip: a functional microcapillary occlusion assay complementary to ektacytometry for detection of small-fraction red blood cells with abnormal …
…, E Kucukal, C Federici, WJ Wulftange… - Frontiers in …, 2022 - frontiersin.org
Red blood cell (RBC) deformability is a valuable hemorheological biomarker that can be used
to assess the clinical status and response to therapy of individuals with sickle cell disease …
to assess the clinical status and response to therapy of individuals with sickle cell disease …
A microfluidic device for assessment of E-selectin-mediated neutrophil recruitment to inflamed endothelium and prediction of therapeutic response in sickle cell …
Neutrophil recruitment to the inflamed endothelium is a multistep process and is of utmost
importance in the development of the hallmark vaso-occlusive crisis in sickle cell disease (SCD…
importance in the development of the hallmark vaso-occlusive crisis in sickle cell disease (SCD…
[HTML][HTML] Human macrophages survive and adopt activated genotypes in living zebrafish
CD Paul, A Devine, K Bishop, Q Xu, WJ Wulftange… - Scientific reports, 2019 - nature.com
The inflammatory response, modulated both by tissue resident macrophages and recruited
monocytes from peripheral blood, plays a critical role in human diseases such as cancer and …
monocytes from peripheral blood, plays a critical role in human diseases such as cancer and …
Spatial control of oxygen delivery to three‐dimensional cultures alters cancer cell growth and gene expression
WJ Wulftange, MA Rose… - Journal of cellular …, 2019 - Wiley Online Library
Commonly used monolayer cancer cell cultures fail to provide a physiologically relevant
environment in terms of oxygen delivery. Here, we describe a three‐dimensional (3D) …
environment in terms of oxygen delivery. Here, we describe a three‐dimensional (3D) …
Decorrelation Time Mapping as an Analysis Tool for Nanobubble-Based Contrast Enhanced Ultrasound Imaging
Nanobubbles (NBs; ~100-500 nm diameter) are preclinical ultrasound (US) contrast agents
that expand applications of contrast enhanced US (CEUS). Due to their sub-micron size, …
that expand applications of contrast enhanced US (CEUS). Due to their sub-micron size, …
Antithrombin‐III mitigates thrombin‐mediated endothelial cell contraction and sickle red blood cell adhesion in microscale flow
Individuals with sickle cell disease (SCD) have persistently elevated thrombin generation
that results in a state of systemic hypercoagulability. Antithrombin‐III (ATIII), an endogenous …
that results in a state of systemic hypercoagulability. Antithrombin‐III (ATIII), an endogenous …
[HTML][HTML] Enteric glial hub cells coordinate intestinal motility
…, KC Letai, Y Maeno-Hikichi, WJ Wulftange… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Enteric glia are the predominant cell type in the enteric nervous system yet their identities and
roles in gastrointestinal function are not well classified. Using our optimized single nucleus …
roles in gastrointestinal function are not well classified. Using our optimized single nucleus …