Many vegetables considered beneficial to human health contain the amino acid derivative, S-methyl-l-cysteine
sulphoxide. This plant secondary metabolite functions as a phytoalexin …

Background:An improved understanding of the contribution of the diet to health and disease
risks requires accurate assessments of dietary exposure in nutritional epidemiologic studies…

Consumption of cruciferous vegetables (CVs) is inversely correlated to many human
diseases including cancer (breast, lung, and bladder), diabetes, and cardiovascular and …

Extraction of meaningful biological information from urinary metabolomic profiles obtained
by liquid-chromatography coupled to mass spectrometry (MS) necessitates the control of …

Although benzene has long been recognized as a cause of human leukemia, the mechanism
by which this simple molecule causes cancer has been problematic. A complicating factor …

Early-life exposures are believed to influence the incidence of pediatric acute lymphoblastic
leukemia (ALL). Archived neonatal blood spots (NBS), collected within the first days of life, …

Background Epidemiologists are beginning to employ metabolomics and lipidomics with
archived blood from incident cases and controls to discover causes of cancer. Although several …

Xuanwei and Fuyuan counties in China have the highest lung cancer rates in the world due
to household air pollution from combustion of smoky coal for cooking and heating. To …

Oxidative stress generates reactive species that modify proteins, deplete antioxidant defenses,
and contribute to chronic obstructive pulmonary disease (COPD) and ischemic heart …

A long-standing challenge of untargeted metabolomic profiling by ultrahigh-performance
liquid chromatography–high-resolution mass spectrometry (UHPLC–HRMS) is efficient …