Our knowledge of the molecular mechanisms of intracellular homeostatic control of zinc ions
is now firmly grounded on experimental findings gleaned from the study of zinc proteomes …

The explicit mathematical model presented by Hodgkin and Huxley (50) provided a giant
step forward in capturing the nonlinear properties of nerve membrane. The effort to increase …

To understand the mechanisms of neuronal Zn 2+ homeostasis better, experimental data
obtained from cultured cortical neurons were used to inform a series of increasingly complex …

Most data analyses rely on models. To complement statistical models, psychologists have
developed cognitive models, which translate observed variables into psychologically …

Eukaryotic cell motility involves complex interactions of signalling molecules, cytoskeleton,
cell membrane, and mechanics interacting in space and time. Collectively, these components …

1. Because induction of associative long-term potentiation (LTP) in the dentate gyrus is
thought to depend on Ca2+ influx through channels controlled by N-methyl-D-aspartate (NMDA) …

Long-term potentiation (LTP) is typically studied using either continuous high-frequency
stimulation or theta burst stimulation. Previous studies emphasized the physiological relevance …

Small cell lung cancer (SCLC) tumors comprise heterogeneous mixtures of cell states,
categorized into neuroendocrine (NE) and non-neuroendocrine (non-NE) transcriptional subtypes…

A critical task in modeling is to determine how well the theoretical assumptions encoded in
a model account for observations. Bayesian methods are an ideal framework for doing just …

Many mathematical models have been proposed for the process of cell polarization. Some
of these are ‘functional models’ that capture a class of dynamical behaviour, whereas others …