[HTML][HTML] KATP channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer's disease–related pathology

J Grizzanti, WR Moritz, MC Pait, M Stanley, SD Kaye… - JCI insight, 2023 - ncbi.nlm.nih.gov
Elevated blood glucose levels, or hyperglycemia, can increase brain excitability and amyloid-β
(Aβ) release, offering a mechanistic link between type 2 diabetes and Alzheimer’s …

[HTML][HTML] The history and innovations of blood vessel anastomosis

WR Moritz, S Raman, S Pessin, C Martin, X Li… - Bioengineering, 2022 - mdpi.com
Surgical technique and technology frequently coevolve. The brief history of blood vessel
anastomosis is full of famous names. While the techniques pioneered by these surgeons have …

Vaso-Lock for sutureless anastomosis in a pig arteriovenous loop model

…, M Zaghloul, S Roberts, R Meade, B Arif, WR Moritz… - Biomaterials, 2024 - Elsevier
A vascular anastomosis is a critical surgical skill that involves connecting blood vessels.
Traditional handsewn techniques can be challenging and resource intensive. To address these …

Evolution of initiation rites during the Austronesian dispersal

RA Bentley, WR Moritz, DJ Ruck… - Science …, 2021 - journals.sagepub.com
As adaptive systems, kinship and its accompanying rules have co-evolved with elements of
complex societies, including wealth inheritance, subsistence, and power relations. Here we …

[HTML][HTML] Point-of-care tissue oxygenation assessment with SnapshotNIR for alloplastic and autologous breast reconstruction

WR Moritz, J Daines, JM Christensen… - … Surgery–Global Open, 2023 - journals.lww.com
Background: In breast reconstruction, mastectomy and free flaps are susceptible to vascular
compromise and tissue necrosis. The SnapshotNIR device (Kent Imaging, Calgary, AB, …

A coin-tossing problem and some related combinatorics

RH Moritz, RC Williams - Mathematics Magazine, 1988 - Taylor & Francis
In this note we analyze a simple coin-tossing game. The arguments use only the most
elementary facts in probability; the reader will, however, have to invest a little patience-say, 10 or …

Surface modification of PEEKs with cyclic peptides to support endothelialization and antithrombogenicity

…, C Martin, JG Ribaudo, X Xia, WR Moritz… - Materials Today …, 2024 - Elsevier
Synthetic polymers are often utilized in the creation of vascular devices, and need to possess
specific qualities to prevent thrombosis. Traditional strategies for this include surface …

[HTML][HTML] Spare-parts free flap reconstruction in polytrauma with limb amputation: Pearls, pitfalls, and an illustrative case report

WR Moritz, AY Ha, G Giatsidis, LM Tatman, M Berkes… - Orthoplastic …, 2022 - Elsevier
Introduction Spare-part free-flap reconstruction involves free tissue transfer from an
unsalvageable extremity for reconstruction of a separate defect. In the setting of traumatic injury, …

From Augmented to Virtual Reality in Plastic Surgery: Blazing the Trail to a New Frontier

…, T Gordon, J Murphy, WR Moritz… - Journal of …, 2023 - thieme-connect.com
Background Augmented reality (AR) and virtual reality (VR)—termed mixed reality—have
shown promise in the care of operative patients. Currently, AR and VR have well-known …

Sulfonylureas target the neurovascular response to decrease Alzheimer's pathology

SL Macauley, MS Stanley, EE Caesar, WR Moritz… - bioRxiv, 2021 - biorxiv.org
Hyperexcitability is a defining feature of Alzheimer’s disease (AD), where aberrant neuronal
activity is both a cause and consequence of AD. Therefore, identifying novel targets that …