User profiles for William W. Agace

william agace

Lund University, Danish Technical University
Verified email at med.lu.se
Cited by 21943

Regional specialization within the intestinal immune system

AM Mowat, WW Agace - Nature Reviews Immunology, 2014 - nature.com
The intestine represents the largest compartment of the immune system. It is continually
exposed to antigens and immunomodulatory agents from the diet and the commensal microbiota…

[HTML][HTML] Human gut-associated lymphoid tissues (GALT); diversity, structure, and function

…, N von Burg, LB Riis, J Spencer, WW Agace - Mucosal …, 2021 - Elsevier
Gut-associated lymphoid tissues (GALT) are the key antigen sampling and adaptive immune
inductive sites within the intestinal wall. Human GALT includes the multi-follicular Peyer's …

Generation of gut‐homing T cells and their localization to the small intestinal mucosa

B Johansson‐Lindbom, WW Agace - Immunological reviews, 2007 - Wiley Online Library
The intestinal mucosa represents the largest body surface toward the external environment
and harbors numerous T lymphocytes that take up resident within the intestinal epithelium or …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

…, D Adam, S Adam‐Klages, WW Agace… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical aspects of …

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions

…, EK Persson, X Liu, T Worbs, WW Agace… - Journal of Experimental …, 2009 - rupress.org
Chemokine receptor CX3CR1 + dendritic cells (DCs) have been suggested to sample
intestinal antigens by extending transepithelial dendrites into the gut lumen. Other studies …

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

…, G Marquez, R Förster, WW Agace - The Journal of …, 2005 - rupress.org
Gut-associated lymphoid tissue (GALT) dendritic cells (DCs) display a unique ability to generate
CCR9 + α 4 β 7 + gut-tropic CD8 + effector T cells. We demonstrate efficient induction of …

Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: epithelial …

…, EC Butcher, DP Andrew, WW Agace - The Journal of …, 2000 - rupress.org
The immune system has evolved specialized cellular and molecular mechanisms for
targeting and regulating immune responses at epithelial surfaces. Here we show that small …

Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans

…, F Powrie, B Johansson-Lindbom, WW Agace - The Journal of …, 2008 - rupress.org
… Coombes, Pia-Lena Berg, Thomas Davidsson, Fiona Powrie, Bengt Johansson-Lindbom,
William W. Agace; Small intestinal CD103 + dendritic cells display unique functional properties …

[PDF][PDF] IRF4 transcription-factor-dependent CD103+ CD11b+ dendritic cells drive mucosal T helper 17 cell differentiation

…, U Håkansson, B Reizis, K Kotarsky, WW Agace - Immunity, 2013 - cell.com
CD103 + CD11b + dendritic cells (DCs) represent the major migratory DC population within
the small intestinal lamina propria (SI-LP), but their in vivo function remains unclear. Here …

Human G protein–coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and …

BA Zabel, WW Agace, JJ Campbell, HM Heath… - The Journal of …, 1999 - rupress.org
TECK (thymus-expressed chemokine), a recently described CC chemokine expressed in
thymus and small intestine, was found to mediate chemotaxis of human G protein–coupled …