User profiles for William Wiley Navarre
William NavarreProfessor of Molecular Genetics, University of Toronto Verified email at utoronto.ca Cited by 8932 |
Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope
WW Navarre, O Schneewind - Microbiology and molecular biology …, 1999 - Am Soc Microbiol
The cell wall envelope of gram-positive bacteria is a macromolecular, exoskeletal organelle
that is assembled and turned over at designated sites. The cell wall also functions as a …
that is assembled and turned over at designated sites. The cell wall also functions as a …
Selective Silencing of Foreign DNA with Low GC Content by the H-NS Protein in Salmonella
Horizontal gene transfer plays a major role in microbial evolution. However, newly acquired
sequences can decrease fitness unless integrated into preexisting regulatory networks. We …
sequences can decrease fitness unless integrated into preexisting regulatory networks. We …
Proteolytic cleavage and cell wall anchoring at the LPXTG motif of surface proteins in Gram‐positive bacteria
WW Navarre, O Schneewind - Molecular microbiology, 1994 - Wiley Online Library
Many surface proteins are thought to be anchored to the cell wall of Gram‐positive bacteria
via their C‐terminus. Cell wall anchoring requires a specific sorting signal, normally located …
via their C‐terminus. Cell wall anchoring requires a specific sorting signal, normally located …
Silencing of xenogeneic DNA by H-NS—facilitation of lateral gene transfer in bacteria by a defense system that recognizes foreign DNA
WW Navarre, M McClelland, SJ Libby… - Genes & …, 2007 - genesdev.cshlp.org
Lateral gene transfer has played a prominent role in bacterial evolution, but the mechanisms
allowing bacteria to tolerate the acquisition of foreign DNA have been incompletely defined. …
allowing bacteria to tolerate the acquisition of foreign DNA have been incompletely defined. …
Regulation of Salmonella typhimurium virulence gene expression by cationic antimicrobial peptides
MW Bader, WW Navarre, W Shiau… - Molecular …, 2003 - Wiley Online Library
Cationic antimicrobial peptides (CAMP) represent a conserved and highly effective
component of innate immunity. During infection, the Gram‐negative pathogen Salmonella …
component of innate immunity. During infection, the Gram‐negative pathogen Salmonella …
Co‐regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ
WW Navarre, TA Halsey, D Walthers… - Molecular …, 2005 - Wiley Online Library
Analysis of the transcriptome of slyA mutant Salmonella enterica serovar Typhimurium revealed
that many SlyA‐dependent genes, including pagC, pagD, ugtL, mig‐14, virK, phoN, pgtE…
that many SlyA‐dependent genes, including pagC, pagD, ugtL, mig‐14, virK, phoN, pgtE…
[HTML][HTML] Multiple enzymatic activities of the murein hydrolase from staphylococcal phage φ11: Identification of a D-alanyl-glycine endopeptidase activity
WW Navarre, H Ton-That, KF Faull… - Journal of Biological …, 1999 - ASBMB
Bacteriophage muralytic enzymes degrade the cell wall envelope of staphylococci to release
phage particles from the bacterial cytoplasm. Murein hydrolases of staphylococcal phages …
phage particles from the bacterial cytoplasm. Murein hydrolases of staphylococcal phages …
Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosis
Bacterial nucleoid-associated proteins play important roles in chromosome organization
and global gene regulation. We find that Lsr2 of Mycobacterium tuberculosis is a unique …
and global gene regulation. We find that Lsr2 of Mycobacterium tuberculosis is a unique …
Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins
H-NS and Lsr2 are nucleoid-associated proteins from Gram-negative bacteria and Mycobacteria,
respectively, that play an important role in the silencing of horizontally acquired foreign …
respectively, that play an important role in the silencing of horizontally acquired foreign …
Pathogen‐induced apoptosis of macrophages: a common end for different pathogenic strategies: Microreview
WW Navarre, A Zychlinsky - Cellular microbiology, 2000 - Wiley Online Library
Microbe–macrophage interactions play a central role in the pathogenesis of many infections.
Several bacterial pathogens induce apoptosis specifically in macrophages, but the …
Several bacterial pathogens induce apoptosis specifically in macrophages, but the …