Zebrafish, a popular organism for studying embryonic development and for modeling human
diseases, has so far lacked a systematic functional annotation program akin to those in …

In recent years, numerous applications have demonstrated the potential of deep learning for
an improved understanding of biological processes. However, most deep learning tools …

Westernized populations are plagued by a plethora of chronic non-infectious degenerative
diseases, termed as “civilization diseases”, like obesity, diabetes, cardiovascular diseases, …

Obesity has reached epidemic proportions and is one of the greatest challenges for public
health in the twenty-first century. The macronutrient composition of diets, in particular the …

Transcription factor (TF)-mediated reprogramming to pluripotency is a slow and inefficient
process, because most pluripotency TFs fail to access relevant target sites in a refractory …

This report postulates a critical role for the quantity and quality of dietary carbohydrate in the
pathogenesis of obesity and the metabolic syndrome. Significant changes in human …

Advances in single-cell technologies enable the routine interrogation of chromatin
accessibility for tens of thousands of single cells, elucidating gene regulatory processes at an …

In a pandemic with a novel disease, disease-specific prognosis models are available only
with a delay. To bridge the critical early phase, models built for similar diseases might be …

Non-communicable diseases, like diabetes, cardiovascular diseases, cancer, stroke, chronic
obstructive pulmonary disease, osteoporosis, arthritis, Alzheimer’s disease and other more …

Benign prostatic hyperplasia and hypertension are common age-related comorbidities.
Although the etiology of benign prostatic hyperplasia (BPH) is still largely unresolved and poorly …