[HTML][HTML] findMySequence: a neural-network-based approach for identification of unknown proteins in X-ray crystallography and cryo-EM
…, AJ Simpkin, DA Leonardo, W Seifert-Davila… - IUCrJ, 2022 - scripts.iucr.org
Although experimental protein-structure determination usually targets known proteins, chains
of unknown sequence are often encountered. They can be purified from natural sources, …
of unknown sequence are often encountered. They can be purified from natural sources, …
Structural insights into human TFIIIC promoter recognition
W Seifert-Davila, M Girbig, L Hauptmann… - Science …, 2023 - science.org
Transcription factor (TF) IIIC recruits RNA polymerase (Pol) III to most of its target genes.
Recognition of intragenic A- and B-box motifs in transfer RNA (tRNA) genes by TFIIIC modules …
Recognition of intragenic A- and B-box motifs in transfer RNA (tRNA) genes by TFIIIC modules …
Identification of unknown proteins in x-ray crystallography and cryo-EM
…, AJ Simpkin, DA Leonardo, W Seifert-Davila… - bioRxiv, 2021 - biorxiv.org
Although experimental protein structure determination usually targets known proteins, chains
of unknown sequence are often encountered. They can be purified from natural sources, …
of unknown sequence are often encountered. They can be purified from natural sources, …
[CITATION][C] Towards structural insights of the voltage-activated potassium channel 1.2 and its interaction with the gating modifier toxin ProTx-I
WHS Dávila - 2019 - pure.mpg.de
… Dávila, Wolfram Heinrich Seifert …
A graph neural network approach to automated model building in cryo-EM maps
Electron cryo-microscopy (cryo-EM) produces three-dimensional (3D) maps of the electrostatic
potential of biological macromolecules, including proteins. At sufficient resolution, the cryo…
potential of biological macromolecules, including proteins. At sufficient resolution, the cryo…
Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters
Structural maintenance of chromosome complexes, such as cohesin, have been implicated
in a wide variety of chromatin-dependent functions such as genome organization, replication…
in a wide variety of chromatin-dependent functions such as genome organization, replication…
[BOOK][B] Novel computational approaches to the determination of protein structures using X-ray crystallography
FS Rodriguez - 2023 - search.proquest.com
The work of this thesis focuses on the development of novel computational methods for the
determination of protein structures through macromolecular X-ray crystallography (MX). …
determination of protein structures through macromolecular X-ray crystallography (MX). …
[PDF][PDF] Structural analysis of snake venom thrombin-like enzymes (SVTLEs) from Bothrops atrox venom, more than just isoforms
…, DAL Cabrejos, D Torrejon, W Seifert-Davila… - Posters, 2023 - researchgate.net
Background SVTLEs are a group of glycosylated monomeric snake venom serine proteases
(SVSP) which constitute the second most abundant group of enzymes in crude venom (1, 2, …
(SVSP) which constitute the second most abundant group of enzymes in crude venom (1, 2, …
Caracterización bioquímica y estructural de una enzima fosfolipasa A2 del veneno de la serpiente peruana Bothrops pictus “Jergón de costa”
WH Seifert Dávila - 2017 - cybertesis.unmsm.edu.pe
Purifica la isoforma ácida presente en el veneno de Bothrops pictus mediante el uso de dos
pasos cromatográficos: CM Sephadex C-50 seguido de Superdex 75 10/300 GL, …
pasos cromatográficos: CM Sephadex C-50 seguido de Superdex 75 10/300 GL, …