[HTML][HTML] MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC
…, J Wang, S Liu, S Wang, Y Cheng, W Zhou… - Journal of Experimental …, 2016 - Springer
Background Lung cancer is the most common malignancies worldwide. However, the detailed
molecular mechanisms underlying lung cancer progression are still not completely clear. …
molecular mechanisms underlying lung cancer progression are still not completely clear. …
[HTML][HTML] MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling
…, Y Meng, W Zhou, Q Shi, H Zhou… - The Journal of …, 2019 - Am Soc Clin Investig
MAPK4 is an atypical MAPK. Currently, little is known about its physiological function and
involvement in diseases, including cancer. A comprehensive analysis of 8887 gene …
involvement in diseases, including cancer. A comprehensive analysis of 8887 gene …
[HTML][HTML] Estrogen receptor beta promotes lung cancer invasion via increasing CXCR4 expression
S Liu, C Hu, M Li, J An, W Zhou, J Guo, Y Xiao - Cell Death & Disease, 2022 - nature.com
Lung cancer is one of the most lethal malignant tumors in the world. The high recurrence
and mortality rate make it urgent for scientists and clinicians to find new targets for better …
and mortality rate make it urgent for scientists and clinicians to find new targets for better …
[HTML][HTML] MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT
Prostate cancer (PCa) is the second leading cause of cancer death in American men.
Androgen receptor (AR) signaling is essential for PCa cell growth/survival and remains a key …
Androgen receptor (AR) signaling is essential for PCa cell growth/survival and remains a key …
[HTML][HTML] MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade
About 15–20% of breast cancer (BCa) is triple-negative BCa (TNBC), a devastating disease
with limited therapeutic options. Aberrations in the PI3K/PTEN signaling pathway are …
with limited therapeutic options. Aberrations in the PI3K/PTEN signaling pathway are …
MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade
Mitogen-activated protein kinase 6 (MAPK6) is an atypical MAPK. Its function in regulating
cancer growth remains elusive. Here, we reported that MAPK6 directly activated AKT and …
cancer growth remains elusive. Here, we reported that MAPK6 directly activated AKT and …
MICAL2 is a novel nucleocytoplasmic shuttling protein promoting cancer invasion and growth of lung adenocarcinoma
W Zhou, Y Liu, Y Gao, Y Cheng, R Chang, X Li, Y Zhou… - Cancer letters, 2020 - Elsevier
MICAL2 is a tumor-promoting factor involved in cell migration, invasion, deformation, and
proliferation not yet fully explored in lung adenocarcinoma (LUAD). This study demonstrated …
proliferation not yet fully explored in lung adenocarcinoma (LUAD). This study demonstrated …
[HTML][HTML] Bioinformatics construction and experimental validation of a cuproptosis-related lncRNA prognostic model in lung adenocarcinoma for immunotherapy …
L Li, Q Cai, Z Wu, X Li, W Zhou, L Lu, B Yi, R Chang… - Scientific Reports, 2023 - nature.com
Cuproptosis is a newly form of cell death. Cuproptosis related lncRNA in lung adenocarcinoma
(LUAD) has also not been fully elucidated. In the present study, we aimed to construct a …
(LUAD) has also not been fully elucidated. In the present study, we aimed to construct a …
Prognostic significance of tumor-associated macrophages polarization markers in lung cancer: a pooled analysis of 5105 patients
B Yi, Y Cheng, R Chang, W Zhou, H Tang… - Bioscience …, 2023 - portlandpress.com
Background: The prognostic significance of tumor-associated macrophages (TAMs) in patients
with lung cancer (LCa) remains controversial. We therefore conducted the present study …
with lung cancer (LCa) remains controversial. We therefore conducted the present study …
[HTML][HTML] Androgen receptor suppresses lung cancer invasion and increases cisplatin response via decreasing TPD52 expression
S Liu, C Hu, M Li, W Zhou, R Wang… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Lung cancer, as the most commonly diagnosed malignancy, still accounts for the leading
cause of cancer-related deaths worldwide. The high rate of mortality and tumor recurrence has …
cause of cancer-related deaths worldwide. The high rate of mortality and tumor recurrence has …