Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease
KE Murphy, AM Gysbers, SK Abbott, N Tayebi, WS Kim… - Brain, 2014 - academic.oup.com
Heterozygous mutations in GBA1, the gene encoding lysosomal glucocerebrosidase, are
the most frequent known genetic risk factor for Parkinson’s disease. Reduced …
the most frequent known genetic risk factor for Parkinson’s disease. Reduced …
Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease
WS Kim, H Li, K Ruberu, S Chan, DA Elliott… - Journal of …, 2013 - Soc Neuroscience
ATP-binding cassette transporter A7 (ABCA7) is expressed in the brain and has been detected
in macrophages, microglia, and neurons. ABCA7 promotes efflux of lipids from cells to …
in macrophages, microglia, and neurons. ABCA7 promotes efflux of lipids from cells to …
[HTML][HTML] Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts
…, S Becker, GM Halliday, M Bennati, WS Kim… - Nature …, 2019 - nature.com
Parkinson’s disease (PD) and Multiple System Atrophy (MSA) are clinically distinctive diseases
that feature a common neuropathological hallmark of aggregated α-synuclein. Little is …
that feature a common neuropathological hallmark of aggregated α-synuclein. Little is …
[HTML][HTML] Lipid pathway alterations in Parkinson's disease primary visual cortex
Background We present a lipidomics analysis of human Parkinson's disease tissues. We have
focused on the primary visual cortex, a region that is devoid of pathological changes and …
focused on the primary visual cortex, a region that is devoid of pathological changes and …
Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies
… Woojin S Kim , Woojin S Kim … FTLD-tau is subdivided into four main pathological subtypes:
Pick’s disease, corticobasal degeneration (CBD), progressive supranuclear palsy (PSP) and …
Pick’s disease, corticobasal degeneration (CBD), progressive supranuclear palsy (PSP) and …
Assessment of Stress Response of the Probiotic Lactobacillus acidophilus
WS Kim, L Perl, JH Park, JE Tandianus, NW Dunn - Current Microbiology, 2001 - Springer
Different aspects of stress response of Lactobacillus acidophilus were investigated. First, the
sublethal and lethal levels of bile, heat, and NaCl stresses were determined. They were 0.05…
sublethal and lethal levels of bile, heat, and NaCl stresses were determined. They were 0.05…
Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells
… Correspondence and requests for reprints to Woojin S. Kim, Prince of Wales Medical … of
denaturation (94C, 30 s), annealing (60C, 30 s) and extension (72C, 30 s), and the PCR products …
denaturation (94C, 30 s), annealing (60C, 30 s) and extension (72C, 30 s), and the PCR products …
Differentiation of Lactococcus lactis subspecies lactis and subspecies cremoris strains by their adaptive response to stresses
WS Kim, J Ren, NW Dunn - FEMS Microbiology Letters, 1999 - academic.oup.com
Lactococcus lactis subspecies lactis (L. lactis ssp. lactis) and Lactococcus lactis subspecies
cremoris (L. lactis ssp. cremoris) were investigated in respect to their response to acid, bile-…
cremoris (L. lactis ssp. cremoris) were investigated in respect to their response to acid, bile-…
Lipid pathway dysfunction is prevalent in patients with Parkinson's disease
Many genetic risk factors for Parkinson’s disease have lipid-related functions and lipid-modulating
drugs such as statins may be protective against Parkinson’s disease. Moreover, the …
drugs such as statins may be protective against Parkinson’s disease. Moreover, the …
DNA methylation of the MAPT gene in Parkinson's disease cohorts and modulation by vitamin E In Vitro
…, Y Huang, GM Halliday, M Hallupp, WS Kim… - Movement …, 2014 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder for which environmental factors
influence disease risk and may act via an epigenetic mechanism. The microtubule‐associated …
influence disease risk and may act via an epigenetic mechanism. The microtubule‐associated …